|Official Full Name||LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3|
|Background||This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.|
|Synonyms||MP1; MAPBP; MAPKSP1; MAP2K1IP1; Ragulator3; ragulator complex protein LAMTOR3; PRO0633; MEK partner 1; OTTHUMP00000161681; OTTHUMP00000219461; MEK binding partner 1; MEK-binding partner 1; MAPK scaffold protein 1; mitogen-activated protein kinase scaffold protein 1; late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; mitogen-activated protein kinase kinase 1 interacting protein 1; mitogen-activated protein kinase kinase 1-interacting protein 1|
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MAPKSP1 involved in several pathways and played different roles in them. We selected most pathways MAPKSP1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAPKSP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
MAPKSP1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by MAPKSP1 itself. We selected most functions MAPKSP1 had, and list some proteins which have the same functions with MAPKSP1. You can find most of the proteins on our site.
MAPKSP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAPKSP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAPKSP1.