• Official Full Name
  • LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
  • Background
  • This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.
  • Synonyms
  • MP1; MAPBP; MAPKSP1; MAP2K1IP1; Ragulator3; ragulator complex protein LAMTOR3; PRO0633; MEK partner 1; OTTHUMP00000161681; OTTHUMP00000219461; MEK binding partner 1; MEK-binding partner 1; MAPK scaffold protein 1; mitogen-activated protein kinase scaffold protein 1; late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; mitogen-activated protein kinase kinase 1 interacting protein 1; mitogen-activated protein kinase kinase 1-interacting protein 1
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAPK Scaffold Protein 1, His-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MAPKSP1 Protein, His-tagged