• Official Full Name
  • nescient helix loop helix 1
  • Background
  • The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).
  • Synonyms
  • NHLH1; nescient helix loop helix 1; HEN1; helix-loop-helix protein 1; bHLHa35; NSCL; NSCL1; Class A basic helix-loop-helix protein 35; HEN-1; HEN1_HUMAN; NSCL-1; OTTHUMP00000031860
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NHLH1, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human nescient helix loop helix 1, His-tagged
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human NHLH1
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NHLH1 Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NHLH1
Source (Host):Species:Human
Product nameRecombinant Human NHLH1 293 Cell Lysate

Protein Function

NHLH1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein dimerization activity, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NHLH1 itself. We selected most functions NHLH1 had, and list some proteins which have the same functions with NHLH1. You can find most of the proteins on our site.
Related Protein
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein ALX1; ZNF79; ETV3; GATA2; ARID3A; NHLH2; HMX3; PHF21B; GATA2A; GATA3
Function protein dimerization activity
Related Protein TCF3B; HES2.2; DNM1; ARNTL; STRA8; ASCL3; NCF4; TFEC; ATOH1; EBF1
Function transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
Related Protein CSRNP2; LMO2; OSR2; NKX2; MYOD1; ELF5; CEBPA; PAX9; HIF1A; MYF5

Interacting Protein

NHLH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NHLH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NHLH1.

NHLH1 Related Articles

Ratie, L; Ware, M; et al. Dynamic expression of Notch-dependent neurogenic markers in the chick embryonic nervous system. FRONTIERS IN NEUROANATOMY 8:-(2014).
Chen, C; Zhang, CL; et al. Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia. BIPOLAR DISORDERS 16:790-799(2014).