This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species.
NPTXR has several biochemical functions, for example, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NPTXR itself. We selected most functions NPTXR had, and list some proteins which have the same functions with NPTXR. You can find most of the proteins on our site.
Function metal ion binding
Related Protein ADCY1; ZBTB41; ZNF404; MB21D1; CRBN; ZNF7; PHLPP1; PGGT1B; MB; ZDHHC16A
NPTXR Related Articles
Gast, H; Muller, A; et al. CD40 activation induces NREM sleep and modulates genes associated with sleep homeostasis. BRAIN BEHAVIOR AND IMMUNITY 27:133-144(2013).
Bottazzi, B; Garlanda, C; et al. The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity. IMMUNOLOGICAL REVIEWS 227:9-18(2009).