This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation.
PCDH11Y has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCDH11Y itself. We selected most functions PCDH11Y had, and list some proteins which have the same functions with PCDH11Y. You can find most of the proteins on our site.
Function calcium ion binding
Related Protein CELSR2; ITSN2A; THBS1; PGS1; MYL3; RASGRP1; SRR; CAPNS1B; CALM1; MMP8