phf7
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  • Official Full Name
  • PHD finger protein 7
  • Background
  • Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.
  • Synonyms
  • PHF7; PHD finger protein 7; HSPC226; NYD SP6; testis development protein NYD-SP6; HSPC045; NYD-SP6; MGC26088; DKFZp434L1850
Cat.#:PHF7-4423RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PHF7 Protein
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Cat.#:PHF7-3409RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PHF7 Protein, His-tagged
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Cat.#:PHF7-3224HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PHF7 293 Cell Lysate
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Protein Function

PHF7 has several biochemical functions, for example, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHF7 itself. We selected most functions PHF7 had, and list some proteins which have the same functions with PHF7. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein SLC26A6; ASPH; ZNF143; SIKE1; PPP6R2; LNX2; KLRB1F; THEMIS2; LRP5; LBX1
Function zinc ion binding
Related Protein BAZ1A; TRIM24; CYLD; NR1I2; ZNF205; ADAM18; RABIF; TNP2; SETDB2; GFI1AB

Interacting Protein

PHF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHF7.
UBE2D4; SRPK1; IKBKG; ARIH2; MDM2; TRIM26; RNF111; DTX3L; TRIM41; RNF34; RNF14