PPP3CB Protein, protein phosphatase 3, catalytic subunit, beta isozyme


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Official Full Name protein phosphatase 3, catalytic subunit, beta isozyme
Background Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform is an enzyme that in humans is encoded by the PPP3CB gene.
Synonyms PPP3CB; protein phosphatase 3, catalytic subunit, beta isozyme; CALNB, protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta); serine/threonine-pro
    • Species :
    • Chicken
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse PPP3CB-13267M Recombinant Mouse PPP3CB Protein Mammalian Cell His
    Rat PPP3CB-4640R Recombinant Rat PPP3CB Protein Mammalian Cell His
    Chicken PPP3CB-2226C Recombinant Chicken PPP3CB Mammalian Cell His
    Zebrafish PPP3CB-2579Z Recombinant Zebrafish PPP3CB Mammalian Cell His

    PPP3CB involved in several pathways and played different roles in them. We selected most pathways PPP3CB participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3CB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway MAP2K4A; RRAS; FGF12A; HRAS; HSC70; CACNB2A; CACNA2D2; NTRK2B; RAC1A; IL1B
    Calcium signaling pathway PHKA2; PLCD4; HTR5A; GNAL; GNA11B; CACNA1H; PDE1A; PRKACG; CALM2A; TNNC1B
    cGMP-PKG signaling pathway ATP1A3; PPP1CC; ROCK2; MEF2D; MEF2B; NPPB; VDAC3; ATP1B3; MYLK; PIK3CA
    Wnt signaling pathway DAAM1B; EP300; FZD3A; CUL1; CCND1; AXIN2; FZD5; FZD3; WNT2; CAMK2G
    Axon guidance ACTR2B; ADAM10; SCN8A; FGF20A; DCC; MAPK1; TRPC4; ABLIM3; ABL1; TRPC5
    VEGF signaling pathway RAC3B; PRKCG; PLCG2; CDC42; HSPB1; PPP3CB; RAC1B; PLCG1; CASP9; RAC3
    Osteoclast differentiation TNFSF11; CSF1R; PPARG; SIRPG; SFPI1; PIK3CB; TGFBR1; NCF1; CYBA; PIK3R1
    Natural killer cell mediated cytotoxicity PTPN6; IFNA8; TNFRSF10A; IFNGR1; Raet1c; GRB2; GZMB; TYROBP; PPP3R2; SHC2
    T cell receptor signaling pathway PTPN6; MAP2K1; TNF; TEC; EVLB; PPP3R1; PIK3R1; CBLB; NFATC3; CD8B
    B cell receptor signaling pathway VAV2; HDAC5; CR2; GSK3B; ITPR2; PDPK1A; INPP5D; CSK; HRAS; DOK1
    Long-term potentiation PLCB4; PPP3CA; MAP2K1; CALM4; MAP2K2; PPP1CA; GRIN2D; PRKCB; EP300; RPS6KA1
    Glutamatergic synapse SLC38A2; GNAI3; SLC1A1; GRIN2D; HOMER1; PLA2G4D; PRKCG; GNG3; GRM5; MAPK1
    Dopaminergic synapse PPP1CC; KCNJ6; PPP2R3A; SLC6A3; CREB5; GNB4; GRIN2B; MAPK11; GNB3; PPP2CA
    Oxytocin signaling pathway PPP1R12B; PRKAA1; CAMK2G; OXTR; MEF2C; CAMK1G; PPP1CC; KRAS; PTGS2; CACNG6
    Glucagon signaling pathway CREB3L3; CAMK2B; PRKACB; PKM; PHKG2; EP300; G6PC3; PRMT1; LDHC; PPP3CB
    Renin secretion PPP3R2; CLCA2; PLCB1; PPP3CA; CALM1; CALML5; REN2; PPP3CC; PPP3R1; CALM4
    Alzheimers disease TNFRSF1A; MAPT; COX5B; NDUFS4; FADD; CALML5; UQCRC1; NDUFA9; PPP3R1; PSEN1
    Amyotrophic lateral sclerosis (ALS) PPP3CC; GRIN2B; GRIN1; TP53; Casp3; BAX; BCL2L1; TNFRSF1B; CASP12; DERL1
    Amphetamine addiction PRKCG; ARC; GRIN2C; CAMK2B; SLC14A2; GRIN1; CALM2; CALML3; PRKCA; GRIN3A
    Tuberculosis Cd209g; CAMK2D; PMAP-36; cgr2b; IFNA16; IFNG; Il23a; Il12b; MAPK10; IFNA13; VDR

    PPP3CB has several biochemical functions, for example, calcium ion binding, calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3CB itself. We selected most functions PPP3CB had, and list some proteins which have the same functions with PPP3CB. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding NOTCH2NL; NELL1; LETM1; S100A3; PCDH2AB12; EFEMP2; CDH19; NOTCH4; DAG1; RASGRP1
    calcium-dependent protein serine/threonine phosphatase activity PPP3CB; PPP3R1; CAMK2G; NETO2
    calmodulin binding CNN1A; RGS16; PNCK; KCNQ3; CAMSAP1; EPB41; MKNK2; MAPKAPK2; SCN5A; MYH1
    calmodulin-dependent protein phosphatase activity PPP3CA; PPM1A; PPP3CB; PPM1F
    drug binding PIGC; PDE2A; CHRNA3; SMO; DAAM2; RARB; P2RX1; PPARA; CHRNB2; SLC6A4A
    enzyme binding CYP3A4; GRIN1; C6orf211; TSPYL1; GSTM1; UGT1A6A; ANK1; ADORA2A; CD4; UGT1A6
    hydrolase activity LYZ2; SPACA5; OTUB1A; PAPL; ACTG2; ALPI.1; SMG6; Cel; TMPRSS4A; PRSS48
    metal ion binding EGR3; SPRTN; SOBPA; HDHD2; FIBCD1; NME6; HSPG2; NUBPL; PVALB6; ITGB1BP3
    phosphoprotein phosphatase activity PPTC7; PPP2CA; CPPED1; DUSP16; PTPN11; PTPRDB; CTDNEP1B; TENC1; DUSP9; PPM1H
    protein binding RPL19; CD27; STAG2; DAB1; Fgf15; DLGAP4; TRP63; MMP15; PCDH18B; VARS2
    protein dimerization activity NUP210; HELT; GGN; NEUROG3; PIP; POLR1D; HPS1; SRFA; HIF1AL; NCF4
    protein heterodimerization activity IRAK3; NR4A2; BAXA; ATF2; BAD; GRIN2A; TOP2A; HIST2H2AA4; KATNB1; TPD52L1
    protein phosphatase 2B binding SOD1; BAD; AKAP5; ATP2B4; SLC9A1; AKAP1; MYOZ2; PPP3CB
    protein serine/threonine phosphatase activity PPM1AA; MTMR4; PPM1E; PPM1N; PPP6C; PDP1; PPP1R15B; CDC14B; PP2D1; PPP2R5D

    PPP3CB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3CB here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3CB.

    Akap5; NFATC1; Akap6; Ppp3r1; Hmga2; Ywhae; Dlg4; Map3k5

    Vasu, S; McClenaghan, NH; et al. Cellular responses of novel human pancreatic beta-cell line, 1.1B4 to hyperglycemia. ISLETS 5:170-177(2013).
    Polovkova, OG; Makeeva, OA; et al. Expression Profiles of Calcineurin Pathway Genes in Myocardium in Relation to Ischemic Heart Remodeling in Humans. MOLECULAR BIOLOGY 47:382-388(2013).

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