regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.
RCBTB2; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2; CHC1L, chromosome condensation 1 like; RCC1 and BTB domain-containing protein 2; CHC1 L; CHC1L; Chromosome condensation 1 like; RCBT2; RCC1 and BTB domain containing protein 2; RCC1 like G exchanging factor; RCC1 like G exchanging factor RLG; Regulator of chromosome condensation (RCC1) and BTB domain containing protein 2; Regulator of chromosome condensation and BTB domain containing protein 2; RLG; CHC1-L; RCC1-like G exchanging factor RLG; regulator of chromosome condensation and BTB domain-containing protein 2
RCBTB2 has several biochemical functions, for example, Ran guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RCBTB2 itself. We selected most functions RCBTB2 had, and list some proteins which have the same functions with RCBTB2. You can find most of the proteins on our site.
Function Ran guanyl-nucleotide exchange factor activity
Related Protein RCBTB2; SERGEF; ALS2; RANGRF; RANBP10; RCC1
Function protein binding
Related Protein FZD10; ACD; PTPN11A; PRR13; NFKBID; MAP3K5; GRAP; FN1; ALOX15; SH2B1
RCBTB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RCBTB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RCBTB2.
FARS2; UBE2I; HSP90AB1; NUDCD2; COPS4
RCBTB2 Related Articles
Creytens, D; van Gorp, J; et al. Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma. VIRCHOWS ARCHIV 465:97-108(2014).
Kang, M; Cho, JW; et al. Fine localization of a new cataract locus, Kec, on mouse chromosome 14 and exclusion of candidate genes as the gene that causes cataract in the Kec mouse. BMB REPORTS 41:651-656(2008).
Armellini, A; Sarasquete, ME; et al. Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma. BRITISH JOURNAL OF HAEMATOLOGY 141:212-215(2008).