• Official Full Name
  • solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
  • Background
  • SLC9A7, also known as (Na+, K+)/H+ exchanger 7 (NHE7), locates predominantly in the trans-Golgi network (TGN) and plays a role in organellar pH homeostasis. By using the yeast two-hybrid system, the secretory carrier membrane protein 2 (SCAMP2) is reveale
  • Synonyms
  • SLC9A7; solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7; solute carrier family 9 (sodium/hydrogen exchanger), isoform 7 , solute carrier family 9 (sodium/hydrogen exchanger), member 7; sodium/hydrogen exchanger 7; NHE7
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human SLC9A7
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SLC9A7 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SLC9A7

Involved Pathway

SLC9A7 involved in several pathways and played different roles in them. We selected most pathways SLC9A7 participated on our site, such as SLC-mediated transmembrane transport, Sodium/Proton exchangers, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC9A7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SLC-mediated transmembrane transport
SLC30A3; SLC15A3; SLC41A1; SLC35B2; SLC1A4; SLC6A20B; SLC17A1; SLC22A18; SLC27A4; SLC29A1A
Sodium/Proton exchangers
SLC9A3.2; SLC9A7; SLC9A6B; SLC9A6A; SLC9A5; SLC9A8; SLC9A3.1; SLC9A9
Transmembrane transport of small molecules
ATP1A1A.2; SLC35A3B; LCN2; TFR1B; SLC29A2; ANO9; SLC30A5; SLC35B3; SLC1A7A; SLC22A7
Transport of inorganic cations/anions and amino acids/oligopeptides
SLC20A1B; SLC20A2; SLC26A3.2; SLC43A2; SLC9A3.2; SLC9A6B; SLC24A6; SLC26A7; SLC17A7A; SLC43A2B

Protein Function

SLC9A7 has several biochemical functions, for example, potassium:proton antiporter activity, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC9A7 itself. We selected most functions SLC9A7 had, and list some proteins which have the same functions with SLC9A7. You can find most of the proteins on our site.
Related Protein
Function potassium:proton antiporter activity
Related Protein SLC9A8; SLC9A7
Function protein binding
Related Protein DLGAP4; NUP50; C14orf104; PLXDC1; APOBEC2A; ANKHD1; C1R; BICD1; CD93; DNAJB6
Function protein homodimerization activity
Related Protein SOD1; PEX7; BCL2L1; CTBP2; PAFAH1B1; CRYBA2; CEBPB; GIPC1; BOK; CD247
Function sodium:proton antiporter activity
Related Protein SLC9A3.2; SLC9A6A; SLC9A3; SLC9A4; SLC9A7; SLC9A9; SLC9A6B; SLC9A3.1; SLC9A5; SLC9A1

SLC9A7 Related Articles

Meda, SA; Narayanan, B; et al. A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort. NEUROIMAGE 60:1608-1621(2012).
Kagami, T; Chen, S; et al. Identification and biochemical characterization of the SLC9A7 interactome. MOLECULAR MEMBRANE BIOLOGY 25:436-U34(2008).