• Official Full Name
  • syntaxin binding protein 5 (tomosyn)
  • Background
  • Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Synonyms
  • STXBP5; syntaxin binding protein 5 (tomosyn); LGL3; LLGL3; Nbla04300; syntaxin-binding protein 5; tomosyn; tomosyn-1; putative protein product of Nbla04300; lethal(2) giant larvae protein homolog 3;
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat STXBP5 Protein

STXBP5 Related Articles

Lillicrap, D; et al. Syntaxin-binding protein 5 exocytosis regulation: differential role in endothelial cells and platelets. JOURNAL OF CLINICAL INVESTIGATION 124:4231-4233(2014).
Ye, SJ; Huang, YJ; et al. Platelet secretion and hemostasis require syntaxin-binding protein STXBP5. JOURNAL OF CLINICAL INVESTIGATION 124:4517-4528(2014).