TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and;mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 (PubMed;12584440)). See also TAS2R10 (MIM 604791).
TAS2R50; taste receptor, type 2, member 50; taste receptor type 2 member 50; T2R51; T2R50; taste receptor type 2 member 51; TAS2R51
TAS2R50 Related Articles
Gees, M; Alpizar, YA; et al. Differential Effects of Bitter Compounds on the Taste Transduction Channels TRPM5 and IP3 Receptor Type 3. CHEMICAL SENSES 39:295-311(2014).
Deane, AM; Rayner, CK; et al. The Effects of Critical Illness on Intestinal Glucose Sensing, Transporters, and Absorption. CRITICAL CARE MEDICINE 42:57-65(2014).
Akao, H; Polisecki, E; et al. KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly. ATHEROSCLEROSIS 220:456-462(2012).