This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
TAS2R8; taste receptor, type 2, member 8; taste receptor type 2 member 8; T2R8; TRB5; Taste receptor, family B, member 5; taste receptor family B member 5
TAS2R8 Related Articles
Maruoka, D; Arai, M; et al. Mosapride Citrate Increases Postprandial Glucagon-Like Peptide-1, Insulin, and Gene Expression of Sweet Taste Receptors. DIGESTIVE DISEASES AND SCIENCES 60:345-353(2015).
Deane, AM; Rayner, CK; et al. The Effects of Critical Illness on Intestinal Glucose Sensing, Transporters, and Absorption. CRITICAL CARE MEDICINE 42:57-65(2014).