them5
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  • Official Full Name
  • thioesterase superfamily member 5
  • Synonyms
  • THEM5; thioesterase superfamily member 5; FLJ37964
Cat.#:THEM5-16742MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse THEM5 Protein
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Cat.#:THEM5-1097HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human THEM5 293 Cell Lysate
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Involved Pathway

THEM5 involved in several pathways and played different roles in them. We selected most pathways THEM5 participated on our site, such as Fatty Acyl-CoA Biosynthesis, Fatty acid, triacylglycerol, and ketone body metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with THEM5 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fatty Acyl-CoA Biosynthesis
ACOT9.2; ACOT8; THEM5; ACOT10; ACOT9; ACSF2; SLC25A1A; ACOT11A; ACOT13; ACOT9.1
Fatty acid, triacylglycerol, and ketone body metabolism
MED9; MED20; TIAM2; CDK19; ACSF2; DGAT1B; AGPAT2; CDK8; ACOT9.2; PPARGC1B
Metabolism
SLC19A2; COX14; CA5B; CYP2V1; PNPLA8; DPEP2; GYG1A; TM9SF1; NUDT10; GLB1L
Metabolism of lipids and lipoproteins
ARV1; GPAT2; MED6; PPARGC1B; AGPAT6; DPEP2; CYP2V1; PPM1LA; CPNE6; INSIG1
Triglyceride Biosynthesis
ACOT9.1; TMEM195; ACOT12; ACOT11B; ACOT7; ACOT11A; ELOVL1A; ACOT11; DGAT1B; ACSF2

Protein Function

THEM5 has several biochemical functions, for example, palmitoyl-CoA hydrolase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by THEM5 itself. We selected most functions THEM5 had, and list some proteins which have the same functions with THEM5. You can find most of the proteins on our site.
Function
Related Protein
Function palmitoyl-CoA hydrolase activity
Related Protein ACOT5; ACOT8; ACOT1; ACOT7; ACOT2; THEM5; THEM4; PPT1; GNPAT; BAAT
Function protein binding
Related Protein UBE2N; NAP1L1; PTPN9; CNTNAP2; GALNT3; DNAJC10; RANBP2; RPS6KA3; UBA5; TRIM21

Interacting Protein

THEM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THEM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of THEM5.
MAGEA11; CARHSP1

THEM5 Related Articles

Auldridge, ME; Guo, YX; et al. Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato. PLANT CELL 24:1596-1607(2012).
Weeks, AM; Coyle, SM; et al. Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity. BIOCHEMISTRY 49:9269-9279(2010).