• Official Full Name
  • trinucleotide repeat containing 6A
  • Background
  • This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
  • Synonyms
  • TNRC6A; trinucleotide repeat containing 6A; TNRC6, trinucleotide repeat containing 6; trinucleotide repeat-containing gene 6A protein; CAGH26; GW182; KIAA1460; EDIE; GW182 autoantigen; CAG repeat protein 26; EMSY interactor protein; glycine-tryptophan pr
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNRC6A protein, His & T7-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tnrc6a protein, His & T7-tagged

TNRC6A Related Articles

Li, SQ; Lian, SL; et al. Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing. JOURNAL OF CELL SCIENCE 121:4134-4144(2008).