• Official Full Name
  • tripartite motif containing 16
  • Background
  • This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined.
  • Synonyms
  • TRIM16; tripartite motif containing 16; tripartite motif-containing protein 16; EBBP; estrogen responsive B box protein; tripartite motif-containing 16; estrogen-responsive B box protein; DKFZp434O1826
Source (Host):Species:Human
Product nameRecombinant Human TRIM16 cell lysate

Protein Function

TRIM16 has several biochemical functions, for example, DNA binding, NACHT domain binding, interleukin-1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM16 itself. We selected most functions TRIM16 had, and list some proteins which have the same functions with TRIM16. You can find most of the proteins on our site.
Related Protein
Function DNA binding
Related Protein HIST1H2AD; TAF1A; RYBPB; ZFP90; HLX1; TBX1; NR4A2A; LBX1B; TXLNB; ABT1
Function NACHT domain binding
Related Protein CARD8; TRIM16
Function interleukin-1 binding
Related Protein A2M; HAX1; TRIM16
Function protein binding
Related Protein DKC1; BCL2A1A; TYROBP; TOP1; YIPF2; SLC25A23; ARAP3; POLR2A; FGF13; XPA
Function zinc ion binding
Related Protein SORD; PDLIM7; RNF185; PCGF5A; FBXL19; ZFP330; KDM5A; RNF214; CD4; RECQL4

Interacting Protein

TRIM16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM16 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM16.
TINF2; VIM; E2F1; TERF1; SETDB1; ACD; POT1; Sidt2; Gnpnat1; Rhoa

TRIM16 Related Articles

Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
Evans, ME; Kumkhaek, C; et al. TRIM5 alpha Variations Influence Transduction Efficiency With Lentiviral Vectors in Both Human and Rhesus CD34+Cells In Vitro and In Vivo. MOLECULAR THERAPY 22:348-358(2014).