|Official Full Name||tripartite motif containing 6|
|Background||The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members.|
|Synonyms||TRIM6; tripartite motif containing 6; tripartite motif-containing protein 6; RNF89; Ring Finger Protein 89; TRIM 6; Tripartite motif containing protein 6; tripartite motif-containing 6|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
TRIM6 involved in several pathways and played different roles in them. We selected most pathways TRIM6 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine Signaling in Immune system||RASGRP1; DUSP7; IFIT12; HBEGF; NUPL2; IFITM3; DUSP9; RASGEF1A; SPTBN1; TRIM22|
|Immune System||RNF135; RBCK1; SIGIRR; RACGAP1; POLR3H; KIF5A; TRIM9; TPP2; LTF; TRAF7|
|Interferon Signaling||TRIM3; IRF4; GBP5; TRIM31; ARIH1L; HLA-DQB2; HERC5; TRIM48; TRIM2; EIF4G2A|
|Interferon gamma signaling||TRIM46; OASL; TRIM62; HLA-DQB2; TRIM48; GBP5; TRIM22; TRIM8; TRIM29; TRIM38|
TRIM6 has several biochemical functions, for example, ligase activity, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM6 itself. We selected most functions TRIM6 had, and list some proteins which have the same functions with TRIM6. You can find most of the proteins on our site.
|ligase activity||UBE2IB; RNF216; TRAF3; EGR2; TRIM58; UHRF1; UBE2NA; TTLL2; NEDD4L; RNF146|
|molecular_function||BSCL2; HIST1H2BD; KBTBD6; SMIM11; CASKIN2; RPZ4; SYNGR3B; MRPS10; TRIM10; TMEM50B|
|protein binding||MAVS; PLK1; ARF1; PPP2CA; ATP1B2; XRCC5; DFFA; DDX39A; CXCR2; LRP2BP|
|protein binding, bridging||CUX1; FSCN3; STUB1; MEN1; BCL3; PSMC6; FLRT2; FSCN1; CNKSR1; TRIM17|
|protein kinase binding||EEF2; DPYSL2; EMP2; SNAP91; AP2A1; PRKAB1; KIF14; PRKCZ; GRB7; DVL1|
|protein tyrosine kinase binding||TRIM6|
|transcription factor binding||DDIT3; MED6; HDAC9; CDK9; NR0B1; NCOA2; HHEX; NKX2; SMAD3; JUND|
|ubiquitin protein ligase activity||RABGEF1; MED24; TMEM189; CBLC; ZNRF1; AKTIP; MED31; MSL2A; MYLIP; ANKIB1|
|zinc ion binding||ZDHHC18B; RBCK1; NR2F6A; WBP4; TRIM63; USP13; RNF181; RABIF; TRAF4; RNF20|
TRIM6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM6.