UCN Protein, urocortin


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Official Full Name urocortin
Background This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to;the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2;receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name;similarity, the product of this gene has no sequence similarity to urotensin II.
Synonyms UCN; urocortin; UI; UROC; UCN1_HUMAN; Urocortin precursor; Urotensin I; OTTHUMP00000122583; urocortin, preproprotein
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UCN-3577H Recombinant Human UCN, GST-tagged E.coli GST
    Mouse UCN-17786M Recombinant Mouse UCN Protein Mammalian Cell His
    Mouse Ucn-274M Recombinant Mouse Ucn Protein, His/GST-tagged E.coli His/GST
    Rat Ucn-275R Recombinant Rat Ucn Protein, His-tagged E.coli His
    Rat UCN-6420R Recombinant Rat UCN Protein Mammalian Cell His
    Rhesus Macaque UCN-5090R Recombinant Rhesus monkey UCN Protein, His-tagged Mammalian Cell His

    UCN involved in several pathways and played different roles in them. We selected most pathways UCN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UCN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    UCN has several biochemical functions, for example, corticotropin-releasing hormone receptor 1 binding, corticotropin-releasing hormone receptor 2 binding, histone deacetylase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UCN itself. We selected most functions UCN had, and list some proteins which have the same functions with UCN. You can find most of the proteins on our site.

    Function Related Protein
    corticotropin-releasing hormone receptor 1 binding GNAO1B; GNAO1A; UCN; CRH; GNAO1; GNAS
    corticotropin-releasing hormone receptor 2 binding UCN3L; UCN3; CRH; UCN2; UCN
    histone deacetylase inhibitor activity UCN; SKI
    neuropeptide hormone activity PYYA; PYY; AVP; C12orf39; NTS; GAL; NPPA; PENK; AGRP; HCRT
    protein binding KCNIP3; P4HA3; PDIA2; UQCC2; ANKFY1; TCEB3B; SIKE1; SMAD5; RAB37; TUBB2A

    UCN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCN here. Most of them are supplied by our site. Hope this information will be useful for your research of UCN.

    Liguori, G; Squillacioti, C; et al. Presence and Distribution of Urocortin and its Receptors in the Epididymis of Alpaca (Vicugna pacos). ANATOMIA HISTOLOGIA EMBRYOLOGIA 44:66-71(2015).
    Squillacioti, C; De Luca, A; et al. Presence and Distribution of Urocortin and Corticotrophin-Releasing Hormone Receptors in the Bovine Thyroid Gland. ANATOMIA HISTOLOGIA EMBRYOLOGIA 43:429-434(2014).

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