• Official Full Name
  • urocortin
  • Background
  • This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to;the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2;receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name;similarity, the product of this gene has no sequence similarity to urotensin II.
  • Synonyms
  • UCN; urocortin; UI; UROC; UCN1_HUMAN; Urocortin precursor; Urotensin I; OTTHUMP00000122583; urocortin, preproprotein
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UCN, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UCN Protein
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ucn Protein, His/GST-tagged
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ucn Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UCN Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UCN Protein, His-tagged

Protein Function

UCN has several biochemical functions, for example, corticotropin-releasing hormone receptor 1 binding, corticotropin-releasing hormone receptor 2 binding, histone deacetylase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UCN itself. We selected most functions UCN had, and list some proteins which have the same functions with UCN. You can find most of the proteins on our site.
Related Protein
Function corticotropin-releasing hormone receptor 1 binding
Related Protein GNAS; CRH; GNAO1; UCN; GNAO1A; GNAO1B
Function corticotropin-releasing hormone receptor 2 binding
Related Protein UCN3; UCN3L; UCN2; UCN; CRH
Function histone deacetylase inhibitor activity
Related Protein UCN; SKI
Function neuropeptide hormone activity
Related Protein AVP; QRFP; PYYA; NPPA; AGRP; HCRT; C12orf39; CRH; PNOC; PYY
Function protein binding
Related Protein SFRP1; CIDEB; ZNF410; BLOC1S1; SKIL; IRF2; EXOSC1; RPN1; PDS5B; BOP1

UCN Related Articles

Liguori, G; Squillacioti, C; et al. Presence and Distribution of Urocortin and its Receptors in the Epididymis of Alpaca (Vicugna pacos). ANATOMIA HISTOLOGIA EMBRYOLOGIA 44:66-71(2015).
Squillacioti, C; De Luca, A; et al. Presence and Distribution of Urocortin and Corticotrophin-Releasing Hormone Receptors in the Bovine Thyroid Gland. ANATOMIA HISTOLOGIA EMBRYOLOGIA 43:429-434(2014).