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ABHD5

  • Official Full Name

    abhydrolase domain containing 5

  • Overview

    The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.
  • Synonyms

    ABHD5; abhydrolase domain containing 5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; CGI 58; NCIE2; lipid droplet-binding protein CGI-58; abhydrolase domain-containing protein 5; CDS; CGI58; IECN2; MGC8731;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ABHD5-9243H Recombinant Human ABHD5, GST-tagged E.coli GST 6-349a.a.
Human ABHD5-9132HCL Recombinant Human ABHD5 293 Cell Lysate HEK293 N/A
Human ABHD5-580HFL Recombinant Full Length Human ABHD5 Protein, C-Flag-tagged Mammalian cells Flag
Human ABHD5-4635H Recombinant Human ABHD5 protein, His-SUMO-tagged E.coli His-SUMO 2-349aa
Human ABHD5-249H Recombinant Human ABHD5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ABHD5-879HF Recombinant Full Length Human ABHD5 Protein, GST-tagged In Vitro Cell Free System GST 349 amino acids
Human ABHD5-249H-B Recombinant Human ABHD5 Protein Pre-coupled Magnetic Beads HEK293
Mouse ABHD5-1134M Recombinant Mouse ABHD5 Protein Mammalian Cell His
Mouse Abhd5-9242M Recombinant Mouse Abhd5, GST-tagged E.coli GST 1-351a.a.
Mouse ABHD5-217M-B Recombinant Mouse ABHD5 Protein Pre-coupled Magnetic Beads HEK293
Mouse ABHD5-217M Recombinant Mouse ABHD5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Abhd5-1472M Recombinant Mouse Abhd5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat ABHD5-423R Recombinant Rat ABHD5 Protein Mammalian Cell His
Rat ABHD5-78R Recombinant Rat ABHD5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ABHD5-78R-B Recombinant Rat ABHD5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ABHD5-192R Recombinant Rhesus monkey ABHD5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ABHD5-21R Recombinant Rhesus Macaque ABHD5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ABHD5-21R-B Recombinant Rhesus Macaque ABHD5 Protein Pre-coupled Magnetic Beads HEK293
Chicken ABHD5-5394C Recombinant Chicken ABHD5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ABHD5 Related Articles

ABHD5 involved in several pathways and played different roles in them. We selected most pathways ABHD5 participated on our site, such as Regulation of lipolysis in adipocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABHD5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of lipolysis in adipocytesPIK3CD;NPY1R;PRKG1;GNAI1;INS2;PTGER3;TSHB;AKT1;GNAS

ABHD5 has several biochemical functions, for example, 1-acylglycerol-3-phosphate O-acyltransferase activity, carboxylic ester hydrolase activity, lysophosphatidic acid acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABHD5 itself. We selected most functions ABHD5 had, and list some proteins which have the same functions with ABHD5. You can find most of the proteins on our site.

Function Related Protein
1-acylglycerol-3-phosphate O-acyltransferase activityAGPAT1;AGPAT4;AGPAT2;ABHD5;AGPAT3;LCLAT1;AGPAT9L;LYCAT;LPCAT2
carboxylic ester hydrolase activityNCEH1A;LIPCA;ABHD2B;Aadacl3;LIPI;ACOT12;FAM135B;ABHD5;Ces2c
lysophosphatidic acid acyltransferase activity
NOT triglyceride lipase activity

ABHD5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABHD5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABHD5.

Dlg4; q81sn0_bacan; q81y62_bacan

Stelmanska, E; Szrok, S; et al. Progesterone-induced down-regulation of hormone sensitive lipase (Lipe) and up-regulation of G0/G1 switch 2 (G0s2) genes expression in inguinal adipose tissue of female rats is reflected by diminished rate of lipolysis. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 147:31-39(2015).
Jebessa, ZH; Worst, B; et al. Protein Kinase A prevents cardiomyocyte hypertrophy through abhydrolase domain containing 5 (ABHD5)-mediated proteolysis of Histone deacetylase 4(HDAC4). CIRCULATION RESEARCH 113:-(2013).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
What species-derived recombinant ABHD5 protein does your company offer? 04/14/2023

We offer recombinant ABHD5 protein of several species, such as human, mouse, rat, rhesus macaque, and chicken.

I am going to buy recombinant human ABHD5 (GST-tag), can I get a discount? 04/14/2023

Discounts are available for first-time purchases and holidays. For specific discounts, please contact our customer service staff.

What is the tissue specificity of ABHD5? 04/14/2023

ABHD5 has low tissue specificity, and its main tissue expression cluster is skin-epidermis development.

What is the molecular function of ABHD5? 04/14/2023

ABHD5 protein has the molecular function of acyltransferase and transferase.

Which expression system does your ABHD5 protein produce from? 04/14/2023

Our recombinant ABHD5 proteins are expressed from E.coli, HEK293, wheat germ, or mammalian cells. If you have additional requirements, we can offer customized protein expression services.

Customer Reviews (1)

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Reviews
08/21/2021

    I have used your recombinant ABHD5 protein to prepare antibodies with very satisfactory results.

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