| Official Full Name | adenylate cyclase 4 |
| Synonyms | ADCY4; adenylate cyclase 4; adenylate cyclase type 4; AC4; ADCY4_HUMAN; Adenylate cyclase type IV; Adenylyl cyclase 4; Adenylyl cyclase; ATP pyrophosphate lyase 4; ATP pyrophosphate lyase; ATP pyrophosphate-lyase 4; mKIAA4004 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
adcy4 involved in several pathways and played different roles in them. We selected most pathways adcy4 participated on our site, such as Purine metabolism, Rap signaling pathway, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with adcy4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | PDE5A; ADCY1A; NT5C1A; ADA; NT5C1B; PDE1B; POLR2B; ENTPD6; PRIM2; PNP6 |
| Rap signaling pathway | RAP1GAP; SIPA1L1; PLCB3; AKT2; FGF14; PARD6A; FGF21; RAPGEF5; PIK3R2; LPAR2 |
| Calcium signaling pathway | NOS3; AKR1C1; CACNA1B; SPHK1; BDKRB2; PHKB; STIM1A; CHRM3; CHRM2A; GNAL |
| cGMP-PKG signaling pathway | VDAC1; SLC8A2; PRKG1; IRS4; SLC25A5; NPPB; CREB5; ROCK1; PIK3R1; CALM4 |
| cAMP signaling pathway | HTR4; GRIN2B; PPP1CA; PIK3CB; RYR2; PIK3R5; LOC100328615; PIK3CG; MLLT4; PIK3R2 |
| Chemokine signaling pathway | CCL21; CXCL14; PRKCB; PRKCD; CCL7; VAV1; GRK5; BCAR1; PIK3R5; MAPK3 |
| Phospholipase D signaling pathway | MS4A2; DGKZ; RRAS2; PLA2G4F; AVPR2; PIK3R1; AKT1; RHOA; PLCG2; FCER1G |
| Oocyte meiosis | CALM; ITPR1; CAMK2B1; PPP1CAA; ANAPC5; FBXW11A; PTTG2; CALM4; CDC16; PPP3CA |
| Adrenergic signaling in cardiomyocytes | MAPK14A; CAMK2B; CALM3B; CAMK2G; TNNC1A; PRKACB; ATP1A3A; ADCY9; CALM2A; MAPK12B |
| Vascular smooth muscle contraction | PRKACB; PRKCA; Adcy4; MAPK3; CACNA1C; CYP4A14; PLA2G12A; PLA2G5; NPR2; PPP1CC |
| Gap junction | ADRB3B; MAPK7; PLCB4; GRB2; TUBB2A; TUBA8L2; TUBA1L; HRAS; GRM1; SOS1 |
| Platelet activation | F2R; ROCK1; SYK; LYN; PIK3CB; MAPK13; FGB; PIK3R3; PPP1CA; PTGIR |
| Circadian entrainment | GNG3; PRKACA; GNB1; KCNJ9; PRKG1; GRIA2; GNG2; CALML5; CALM4; CACNA1G |
| Retrograde endocannabinoid signaling | PLCB4; GABRA6; MAPK3; GNG3; SLC17A8; GABRQ; GNAI3; PRKCB; ITPR3; GRIA4 |
| Glutamatergic synapse | GNGT2; PPP3CC; GRIN3B; MAPK3; PLA2G4A; GNG8; Adcy4; GNAO1; DLGAP1; SLC1A3 |
| Cholinergic synapse | PIK3R2; PRKCA; GNB3; CHRM4; KRAS; CAMK2G; KCNQ1; KCNQ4; JAK2; PIK3R3 |
| GABAergic synapse | GNGT2; Adcy4; PRKACG; GNG13; GABRA1; GNG11; GABBR1; GABRB3; GAD1; SLC12A5 |
| Taste transduction | TAS2R108; KCNB1; GNG3; PRKACA; TAS2R13; GNB3; TAS2R137; GNB1; ITPR3; TAS2R106 |
| Inflammatory mediator regulation of TRP channels | NGF; ALOX12E; Adcy4; CYP2C37; CALM4; PIK3CB; MAPK13; ASIC5; HTR2B; TRPV4 |
| Insulin secretion | GCG; KCNMB4; KCNMB1; RIMS2; VAMP2; GNA11; CAMK2G; ITPR3; CREB3L1; STX1A |
| GnRH signaling pathway | GNRH3; CACNA1C; MAPK1; PRKACA; MAPK8A; CALML3; MAPK8; PLD2; CAMK2D1; GNRHR1 |
| Ovarian steroidogenesis | PLA2G4A; HSD17B1; LDLR; ACOT2; HSD17B7; AKR1C3; PTGS2; CYP2J6; IGF1; Adcy4 |
| Progesterone-mediated oocyte maturation | MAPK10; MAPK3; PIK3R3B; AKT3A; ANAPC11; BUB1; MAD1L1; IGF1RA; MOS; MAPK14A |
| Estrogen signaling pathway | GNAI2; HSPA1B; KCNJ9; CALML3; MAPK3; SP1; GRM1; SHC4; GABBR1; CALM1 |
| Melanogenesis | CALM2B; PLCB2; POMCA; MC1R; CREB3L1; TCF7L1A; GNA11A; WNT2B; CREB3L3A; HRAS |
| Thyroid hormone synthesis | TTF2; CREB3L2; ATP1B1; GPX8; ASGR2; PLCB3; GPX6; ATP1A3; PRKACG; GNAQ |
| Oxytocin signaling pathway | PRKAG2; MAPK7; KCNJ14; MAPK1; CAMK1G; RYR1; MEF2C; PRKACB; ACTB; CAMK2G |
| Regulation of lipolysis in adipocytes | GNAI3; AQP7; IRS2; IRS4; NPY; PNPLA2; GNAS; GNAI2; IRS1; AKT2 |
| Aldosterone synthesis and secretion | CYP21A1; HSD3B6; STAR; CYP21A2; CALM4; CREB3L3; PRKCA; CAMK2A; CALM2; CREB3L4 |
| Salivary secretion | PLCB2; AMY1A; Adcy4; HTN1; BEST2; PLCB3; PRKACB; CALM4; RYR3; PRKG2 |
| Gastric acid secretion | CA2; ATP1B4; KCNQ1; KCNK10; CAMK2G; PRKACG; KCNJ15; ATP1A1; CALM3; CCKBR |
| Pancreatic secretion | RAB27B; Adcy4; RAP1A; Cel; PLA2G12A; PLA2G3; GNAQ; CCKAR; RYR2; RAB8A |
| Bile secretion | SLC2A1; NR0B2; AQP8; FXYD2; RXRA; ATP1B4; SLCO1A4; ADCY7; ATP1A3; ABCG8 |
| Morphine addiction | GNAI2; GRK4; PRKACB; ARRB1; Adcy4; GNB1; GABBR1; GABRR2; GABRP; PDE7A |
| HTLV-I infection | TBPL1; SMAD3; MYBL1; IL15RA; TNF; SLC25A31; VDAC2; WNT11; WNT8B; LCK |
| Pathways in cancer | STAT5A; IGF1R; WNT10B; MITF; F2RL3; FGF18; LAMA3; Pdgfa&Pdgfb; AXIN1; EGLN1 |
| Dilated cardiomyopathy | ACTC1; ADRB1; RYR2; TNNC1; EMD; ITGA3; ITGB1; CACNA2D1; LMNA; ITGA7 |
adcy4 has several biochemical functions, for example, ATP binding, G-protein beta/gamma-subunit complex binding, adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by adcy4 itself. We selected most functions adcy4 had, and list some proteins which have the same functions with adcy4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | IPPK; KIF1B; ABCA4; SGK196; MYH9; FYN; LIG4; NLRP1; KARS; DYRK4 |
| G-protein beta/gamma-subunit complex binding | GNAT1; GNAZ; GNAT2; GNA11B; GNA15; GNA13A; PIK3R5; GNA15.1; GNA11A; GNAI3 |
| adenylate cyclase activity | ADCY7; GNAS; ADCY6; ADCY9; ADCY1A; ADCY1B; ADCY1; ADCY2B; Adcy4; ADCY3 |
| metal ion binding | ESR2A; ZBED6; FOXP2; ZDHHC3B; SIRT1; HBAE1; RASA4; ZFP426; KLF17; ASPA |
| nucleotide binding | RBFOX1L; STK30; CSF1RA; SMG1; ARL4AA; CELF3; TDRD12; RAB7; MXC; CSNK1DB |
adcy4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with adcy4 here. Most of them are supplied by our site. Hope this information will be useful for your research of adcy4.
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