adgrl3

ADGRL3 exhibits a distinct expression pattern in the central nervous system, showing both regional and cell-type specificity, with prominent expression in [specific brain regions or neuronal populations].

Pharmacological agents or genetic manipulations targeting ADGRL3 can modulate neuronal phenotypes and synaptic plasticity, offering potential avenues for [specific therapeutic interventions or experimental investigations].

The expression of ADGRL3 is tightly regulated during neurodevelopment, involving specific transcription factors and signaling pathways, such as [specific factors or pathways].

Activation of ADGRL3 has functional consequences, influencing crucial processes like neuronal migration, axon guidance, and synaptic connectivity, contributing to [specific outcomes or neuronal circuit formation].

The activity of ADGRL3 can be modulated by post-translational modifications, which impact its downstream signaling and cellular functions, including [specific modifications or their effects].

ADGRL3 plays a role in neurodevelopmental disorders, including ADHD, ASD, and schizophrenia, with underlying mechanisms involving [specific molecular pathways or neural circuit dysregulation], providing insights into its contribution to [relevant disorder pathogenesis or phenotypic manifestations].

ADGRL3 interacts with other cell surface receptors or adhesion molecules, influencing synaptic organization and connectivity, suggesting potential crosstalk between [specific receptors or molecules] and its implications for [relevant synaptic processes].

ADGRL3 interacts with specific ligands or extracellular matrix components, leading to the activation of downstream signaling pathways, such as [specific signaling cascades or pathways].

ADGRL3 signaling interacts with neurotransmitter systems, such as dopamine or glutamate, influencing behavioral and cognitive processes, suggesting involvement in [specific neurochemical systems or related functions].

Identified genetic variations or mutations in ADGRL3 have been associated with neurodevelopmental disorders or psychiatric conditions, such as [specific disorders or phenotypic traits], shedding light on its role in [relevant disease mechanisms or phenotypic variations].