Akr1b7
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Official Full Name
aldo-keto reductase family 1, member B7
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Synonyms
Avdp; MVDP; Akr1b14;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Mouse
- Rat
- HEK293
- Mammalian Cell
- His
- Fc
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Mouse | AKR1B7-1493M | Recombinant Mouse AKR1B7 Protein | Mammalian Cell | His |
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| Mouse | AKR1B7-436M | Recombinant Mouse AKR1B7 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Mouse | AKR1B7-436M-B | Recombinant Mouse AKR1B7 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | AKR1B7-597R | Recombinant Rat AKR1B7 Protein | Mammalian Cell | His |
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| Rat | AKR1B7-253R-B | Recombinant Rat AKR1B7 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | AKR1B7-253R | Recombinant Rat AKR1B7 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
Akr1b7 involved in several pathways and played different roles in them. We selected most pathways Akr1b7 participated on our site, such as Pentose and glucuronate interconversions, Fructose and mannose metabolism, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1b7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pentose and glucuronate interconversions | UGT2A1;UGT1A4;CRYL1;RPE;ALDH3A2A;UGDH;UGT1A1;OXSR1;DHDHL |
| Fructose and mannose metabolism | PMM2;PFKMB;FPGT;TPI1;ALDOAB;HK3;ALDOCB;TSTA3;FBP1A |
| Galactose metabolism | AKR1B1;Akr1b3;G6PC3;G6PCA.2;G6PC2;B4GALT2;GLB1;PFKMA;AKR1B7 |
| Glycerolipid metabolism | LPIN2;CEL.1;LYCAT;ALDH2.2;AGPAT5;AKR1B1;DAK;AGPAT1;LIPG |
| Metabolic pathways | GOT1;MTHFD1B;PYCR2;BCKDHB;NADSYN1;GAL3ST1;ST6GAL2A;THTPA;HSD17B6 |
Akr1b7 has several biochemical functions, for example, alditol:NADP+ 1-oxidoreductase activity, oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1b7 itself. We selected most functions Akr1b7 had, and list some proteins which have the same functions with Akr1b7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alditol:NADP+ 1-oxidoreductase activity | AKR7A2;AKR1B1;AKR1C2;AKR7A5;AKR1B7;Akr1b3;AKR1C21;PRKRA;ADH4 |
| oxidoreductase activity | PYCR1B;HSD17B12B;FADS6;CYP1C2;CYP2J6;C10orf33;ALDH2.1;ERO1L;CYP2C54 |
Akr1b7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1b7 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1b7.
- Reviews
- Q&As
Customer Reviews (4)
Write a reviewThe functional activity of AKR1B7 was verified by several methods, and the results were consistent and reliable.
The quality of AKR1B7 was stable and reliable, and there was no significant difference between different batches.
Good solubility and is easy to manipulate and purify.
AKR1B7 has a wide range of applications in scientific research and is suitable for a variety of experimental designs and research purposes.
Q&As (15)
Ask a questionAKR1B7 protein is closely related to the occurrence and development of diabetes mellitus and is involved in a variety of enzyme reactions in the glucose metabolism pathway, especially the regulation of glucose-ketose isomerase and aldose reductase.
AKR1B7 protein is involved in the metabolism of polysaccharide and mannose, and has a certain regulation effect on blood glucose level.
The development of AKR1B7 inhibitors may be expected to be an effective treatment for cancer treatment and metabolic diseases such as diabetes.
AKR1B7 protein may have a certain relationship with the occurrence and development of cancer, especially pancreatic, breast, colorectal, lung and other cancers.
AKR1B7 protein is involved in the metabolism of polysaccharides and other substances, and may also have antioxidant and neuroprotective effects.
AKR1B7 protein is involved in the occurrence and development of cardiovascular disease in multiple aspects including vascular function, oxidative stress and inflammation.
Current studies suggest that AKR1B7 protein is involved in the regulation of autophagy, metabolic reprogramming and tumor microenvironment in some tumor cells, thus participating in tumor proliferation and metastasis.
AKR1B7 protein can be involved in the treatment and prevention of neurodegenerative diseases by inhibiting ROS production, anti-neuronal apoptosis, inhibiting NF-κB and other mechanisms.
AKR1B7 protein can promote the dehydrogenase reaction of fatty acids, increase liver fatty acid synthesis, and lead to the occurrence and development of nonalcoholic fatty liver disease.
AKR1B7 protein is an aldose reductase, which is mainly involved in the metabolic process of polysaccharides, polyphenols, steroids, etc.
AKR1B7 protein has been associated with metabolic diseases such as diabetes, non-alcoholic fatty liver disease, neurodegenerative diseases, tumors, etc.
AKR1B7 protein may be involved in processes such as oxidative stress and inflammation in the liver, thereby affecting liver metabolism and function.
AKR1B7 protein is involved in a variety of cellular signaling pathways, such as NF-κB, MAPK, PI3K/Akt and other signaling pathways.
AKR1B7 mutation and polymorphism are related to the occurrence and development of metabolic diseases such as diabetes and a variety of cancers.
AKR1B7 protein is mainly detected in laboratory by Western blotting and enzyme-linked immunosorbent assay.
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