ANXA8L1

There is limited information available regarding genetic variants or mutations in the ANXA8L1 gene. Comprehensive studies exploring ANXA8L1 gene variations and their associations with diseases are needed to better understand the genetic landscape of ANXA8L1.

The involvement of ANXA8L1 in diseases is not well-established and requires further investigation. However, emerging evidence suggests that dysregulation of ANXA8L1 expression or function may be implicated in certain cancers, neurodegenerative disorders, and cardiovascular diseases.

Research on ANXA8L1's protein-protein interactions is limited. However, it has been reported to interact with other annexin family members, such as ANXA2. Further investigations are needed to uncover additional interacting partners and understand the functional consequences of these interactions.

ANXA8L1 is known to be expressed in several tissues, including the brain, heart, liver, lung, kidney, testis, and intestines. Its expression patterns may vary across different tissues and cell types, indicating potential tissue-specific functions.

Although specific post-translational modifications (PTMs) of ANXA8L1 have not been extensively studied, it is plausible that PTMs, such as phosphorylation, acetylation, or ubiquitination, may regulate its function and localization. However, further research is required to elucidate the PTMs that regulate ANXA8L1.