ANXA8L2
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Official Full Name
annexin A8-like 2
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Overview
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. -
Synonyms
ANXA8L2; annexin A8-like 2; annexin A8-like protein 2; bA145E20.2; annexin A8L2; ANXA8;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ANXA8L2-6845H | Recombinant Human Annexin A8-Like 2, His-tagged | E.coli | His | 1-327aa |
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| Human | ANXA8L2-9701H | Recombinant Human ANXA8L2, GST-tagged | E.coli | GST | 130-200 | |
| Human | ANXA8L2-28HCL | Recombinant Human ANXA8L2 lysate | HEK293 | Non |
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| Human | ANXA8L2-4531H | Recombinant Human ANXA8L2 protein, GST-tagged | E.coli | GST | 1-276aa |
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ANXA8L2 involved in several pathways and played different roles in them. We selected most pathways ANXA8L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA8L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ANXA8L2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA8L2 itself. We selected most functions ANXA8L2 had, and list some proteins which have the same functions with ANXA8L2. You can find most of the proteins on our site.
| Function | Related Protein |
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ANXA8L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA8L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA8L2.
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Customer Reviews (4)
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Q&As (5)
Ask a questionThe involvement of ANXA8L2 in diseases is not well-established and requires further study. However, recent research suggests that ANXA8L2 may be implicated in certain cancers and cardiovascular diseases. Additional research is needed to understand the exact role of ANXA8L2 in disease processes.
There is limited information available regarding the protein-protein interactions of ANXA8L2. However, it is likely to interact with other annexin family members and potentially other binding partners. Further investigations are needed to identify specific interacting proteins and uncover their functional significance.
The specific post-translational modifications (PTMs) of ANXA8L2 have not been extensively studied. Nevertheless, similar to other annexin proteins, ANXA8L2 may undergo PTMs, such as phosphorylation, acetylation, or ubiquitination, that could regulate its function. Further research is required to uncover the PTMs that modulate ANXA8L2.
Limited information is available regarding genetic variants or mutations in the ANXA8L2 gene. Comprehensive studies exploring ANXA8L2 gene variations and their associations with diseases are necessary to gain insights into the genetic landscape of ANXA8L2.
The functions of ANXA8L2 are not well-understood, and additional research is necessary. However, studies suggest that ANXA8L2 may play a role in calcium-dependent membrane processes, such as membrane organization, vesicular trafficking, and membrane repair. It may also be involved in cellular processes such as cell growth, differentiation, and apoptosis.
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