• Official Full Name

    annexin A8-like 2

  • Background

    This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
  • Synonyms

    ANXA8L2; annexin A8-like 2; annexin A8-like protein 2; bA145E20.2; annexin A8L2; ANXA8;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANXA8L2-6845H Recombinant Human Annexin A8-Like 2, His-tagged E.coli His
    Human ANXA8L2-4531H Recombinant Human ANXA8L2 protein, GST-tagged E.coli GST
    Human ANXA8L2-9701H Recombinant Human ANXA8L2, GST-tagged E.coli GST
    Human ANXA8L2-28HCL Recombinant Human ANXA8L2 lysate HEK293 N/A
    • Q&As
    • Reviews

    Q&As (5)

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    Is ANXA8L2 associated with any diseases? 04/17/2020

    The involvement of ANXA8L2 in diseases is not well-established and requires further study. However, recent research suggests that ANXA8L2 may be implicated in certain cancers and cardiovascular diseases. Additional research is needed to understand the exact role of ANXA8L2 in disease processes.

    Are there any known interactions of ANXA8L2 with other proteins? 01/15/2019

    There is limited information available regarding the protein-protein interactions of ANXA8L2. However, it is likely to interact with other annexin family members and potentially other binding partners. Further investigations are needed to identify specific interacting proteins and uncover their functional significance.

    Can ANXA8L2 be regulated by post-translational modifications? 05/14/2018

    The specific post-translational modifications (PTMs) of ANXA8L2 have not been extensively studied. Nevertheless, similar to other annexin proteins, ANXA8L2 may undergo PTMs, such as phosphorylation, acetylation, or ubiquitination, that could regulate its function. Further research is required to uncover the PTMs that modulate ANXA8L2.

    Are there any known genetic variants or mutations in the ANXA8L2 gene? 11/05/2017

    Limited information is available regarding genetic variants or mutations in the ANXA8L2 gene. Comprehensive studies exploring ANXA8L2 gene variations and their associations with diseases are necessary to gain insights into the genetic landscape of ANXA8L2.

    What are the known functions of ANXA8L2? 02/07/2017

    The functions of ANXA8L2 are not well-understood, and additional research is necessary. However, studies suggest that ANXA8L2 may play a role in calcium-dependent membrane processes, such as membrane organization, vesicular trafficking, and membrane repair. It may also be involved in cellular processes such as cell growth, differentiation, and apoptosis.

    Customer Reviews (4)

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