AP1M1
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Official Full Name
adaptor-related protein complex 1, mu 1 subunit -
Overview
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. -
Synonyms
AP1M1;adaptor-related protein complex 1, mu 1 subunit;AP-1 complex subunit mu-1;AP47;CLAPM2;Adaptor protein complex AP-1 mu-1 subunit;Adaptor-related protein complex 1 mu-1 subunit;AP-mu chain family member mu1A;AP1M1_HUMAN;Clathrin adaptor protein AP47;Clathrin assembly protein complex 1 medium chain 1;Clathrin assembly protein complex 1 medium chain;Clathrin assembly protein complex AP1 mu subunit;Clathrin coat assembly protein AP47;Clathrin coat-associated protein AP47;CLTNM;Golgi adaptor AP 1 47 kDa protein;Golgi adaptor HA1/AP1 adaptin mu-1 subunit;HA1 47 kDa subunit;MU 1A;Mu-adaptin 1;Mu1A-adaptin;golgi adaptor AP-1 47 kDa protein;clathrin assembly protein complex 1, medium chain;clathrin assembly protein complex AP1, mu subunit;MU-1A
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- GST
- His
- Avi
- Fc
Involved Pathway
AP1M1 involved in several pathways and played different roles in them. We selected most pathways AP1M1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1M1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | CTNS,AP3S2,GM2A,ATP6AP1B,DNASE2A,LAPTM4B,ATP6V0CB,IDUA,CTSE,CTSL1B |
Protein Function
AP1M1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1M1 itself. We selected most functions AP1M1 had, and list some proteins which have the same functions with AP1M1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RB1,RNMT,MAPK7,FRK,RGS19,COG3,ELP3,SRP14,IYD,TRPC7 |
Interacting Protein
AP1M1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1M1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1M1.
FXR2;RUNDC3A;ZBTB8A;TIFA;LDOC1;MTF1
Resources
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References
- Sawasdee, N; Junking, M; et al. Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 mu 1A (AP-1 mu1A). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 401:85-91(2010).
