AP1M1

  • Official Full Name

    adaptor-related protein complex 1, mu 1 subunit

  • Overview

    The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
  • Synonyms

    AP1M1; adaptor-related protein complex 1, mu 1 subunit; AP-1 complex subunit mu-1; AP47; CLAPM2; Adaptor protein complex AP-1 mu-1 subunit; Adaptor-related protein complex 1 mu-1 subunit; AP-mu chain family member mu1A; AP1M1_HUMAN; Clathrin adaptor protein AP47; Clathrin assembly protein complex 1 medium chain 1; Clathrin assembly protein complex 1 medium chain; Clathrin assembly protein complex AP1 mu subunit; Clathrin coat assembly protein AP47; Clathrin coat-associated protein AP47; CLTNM; Golgi adaptor AP 1 47 kDa protein; Golgi adaptor HA1/AP1 adaptin mu-1 subunit; HA1 47 kDa subunit; MU 1A; Mu-adaptin 1; Mu1A-adaptin; golgi adaptor AP-1 47 kDa protein; clathrin assembly protein complex 1, medium chain; clathrin assembly protein complex AP1, mu subunit; MU-1A;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AP1M1-9710H Recombinant Human AP1M1, GST-tagged E.coli GST C-term-260a.a.
Human AP1M1-647H Recombinant Human AP1M1 protein, GST-tagged Wheat Germ GST
Human AP1M1-0462H Recombinant Human AP1M1 Protein (Met1-Pro258), N-His-tagged E.coli N-His Met1-Pro258
Human AP1M1-1080HF Recombinant Full Length Human AP1M1 Protein, GST-tagged In Vitro Cell Free System GST 423 amino acids
Human AP1M1-182H Recombinant Human AP1M1 Protein, His-tagged E.coli N-His Ser2-Pro258
Mouse Ap1m1-3528M Recombinant Mouse Ap1m1, His-tagged E.Coli or Yeast His 423
Mouse AP1M1-1733M Recombinant Mouse AP1M1 Protein Mammalian Cell His
Mouse AP1M1-596M Recombinant Mouse AP1M1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse AP1M1-596M-B Recombinant Mouse AP1M1 Protein Pre-coupled Magnetic Beads HEK293
Rat AP1M1-699R Recombinant Rat AP1M1 Protein Mammalian Cell His
Rat AP1M1-355R-B Recombinant Rat AP1M1 Protein Pre-coupled Magnetic Beads HEK293
Rat AP1M1-355R Recombinant Rat AP1M1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque AP1M1-345R Recombinant Rhesus monkey AP1M1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque AP1M1-173R-B Recombinant Rhesus Macaque AP1M1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque AP1M1-173R Recombinant Rhesus Macaque AP1M1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken AP1M1-1789C Recombinant Chicken AP1M1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

AP1M1 involved in several pathways and played different roles in them. We selected most pathways AP1M1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1M1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
LysosomeLAMP2;CTSJ;FAM49BA;CLTCA;LAMP1;AP3S2;CTSL1B;IGF2R;GM2A

AP1M1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1M1 itself. We selected most functions AP1M1 had, and list some proteins which have the same functions with AP1M1. You can find most of the proteins on our site.

Function Related Protein
protein bindingC8orf33;USP47;MID2;PPP1R12A;NANOS3;PEX14;FLOT2;CACYBP;ITGAV

AP1M1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1M1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1M1.

FXR2; RUNDC3A; ZBTB8A; TIFA; LDOC1; MTF1

Research Area

Related articles

Sawasdee, N; Junking, M; et al. Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 mu 1A (AP-1 mu1A). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 401:85-91(2010).
  • Reviews
  • Q&As

Customer Reviews (4)

Write a review
Reviews
09/29/2022

    It has the characteristics of short half-life and high clearance, which makes it act quickly in the body and clear quickly, improving the efficiency of treatment.

    06/21/2021

      Unmatched repeatability and highly consistent performance under all conditions make it ideal for use in experiments or applications that require a high degree of repeatability.

      03/12/2021

        Stability is very good, after many repeated use, its performance remains stable, showing good product quality.

        03/05/2019

          The production process has minimal impact on the environment and truly achieves green production.

          Q&As (19)

          Ask a question
          What is the application prospect of recombinant AP1M1 in the field of cell therapy? 12/12/2022

          It is still in the research stage, and further experiments and clinical trials are needed to determine the application prospects of AP1M1 in the field of cell therapy.

          What is the structure of AP1M1 ? 10/08/2022

          The structure of AP1M1 is a polypeptide chain, consisting of multiple amino acid residues, which contain a number of functional domains. The specific structure varies depending on the sample source and preparation method.

          Clinical dose of AP1M1 ? 03/11/2022

          A standard dose of AP1M1 has not yet been determined, and this will require further clinical trials to determine.

          What is the action mechanism of AP1M1 ? 02/04/2022

          The mechanism of action of AP1M1 is to achieve therapeutic effects by regulating pathways such as intracellular protein transport and membrane topology maintenance.

          Recombinant AP1M1 is used in the treatment of what diseases? 01/25/2022

          At present, the clinical application of AP1M1 is still in the research stage, but its potential use includes the treatment of some cancers, autoimmune diseases and so on.

          Can recombinant AP1M1 induce immune response? 01/09/2022

          No AP1M1 has been found to induce a significant immune response, but allergies need to be checked frequently.

          Is AP1M1 toxic? 06/01/2021

          At present, there is no toxicity problem of AP1M1 in clinical treatment. However, in the process of use, the patient's physical condition and allergies and other factors need to be considered.

          Is there any side effect of the application of AP1M1 ? 05/19/2021

          In clinical treatment, adverse reactions of AP1M1 are rare, but side effects such as allergic reactions may occur.

          In what medical fields can recombinant AP1M1 be applied? 01/29/2021

          In addition to areas currently being explored such as cancer and autoimmune diseases, the recombinant AP1M1 protein has potential applications in areas such as neurological diseases and metabolic diseases.

          What is the production process of AP1M1 ? 12/30/2020

          The production process of AP1M1 includes protein expression, cell culture, protein purification, quality control and storage.

          Does AP1M1 have broad spectrum? 10/07/2020

          The specific role of the AP1M1 remains to be studied, but its wide distribution within cells suggests that it may have broad-spectrum effects.

          How is AP1M1 prepared? 09/10/2020

          The recombinant AP1M1 protein can be expressed and purified in cells or cell culture through genetic engineering technology.

          What is AP1M1 ? 08/23/2020

          The AP1M1 is a protein encoded by the AP1M1 gene in the human protein-coding genome. It is responsible for participating in many important biological processes within the cell, such as protein transport and cell membrane topology maintenance.

          What is the development trend of AP1M1 in the future? 07/06/2020

          With further research and clinical trials of AP1M1 , it is expected to become a new therapeutic means and bring great help for the treatment of related diseases.

          How is the AP1M1 tolerated? 04/22/2020

          There are currently no large-scale tolerance studies, but short-term clinical trial results show that the AP1M1 is widely tolerated.

          Can AP1M1 be used with other drugs? 11/27/2019

          Further studies are needed to determine the pharmacokinetic and pharmacodynamic interactions of recombinant AP1M1 with other drugs.

          What is the research status of AP1M1 ? 11/26/2019

          At present, the research of AP1M1 is still relatively preliminary, and further clinical trials and basic research are needed to determine its clinical application prospects.

          What are the dosage forms of AP1M1 ? 06/04/2019

          At present, the dosage form of AP1M1 has not been determined, and further studies are needed to determine it.

          What is the effect of AP1M1 ? 04/16/2019

          The efficacy of AP1M1 in clinical trials needs to be further demonstrated, but the current preliminary study shows its potential therapeutic effect.

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