AP4E1 involved in several pathways and played different roles in them. We selected most pathways AP4E1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP4E1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Lysosome |
AP1S2; AP3S1; GLB1; NPC2; ASAH1; MAN2B1; GNPTAB; NAGA; ARSA; GGA3 |
AP4E1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AP4E1 itself. We selected most functions AP4E1 had, and list some proteins which have the same functions with AP4E1. You can find most of the proteins on our site.
AP4E1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP4E1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP4E1.
Abdollahpour, H; Alawi, M; et al. An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome. EUROPEAN JOURNAL OF HUMAN GENETICS 23:256-259(2015).
Tuysuz, B; Bilguvar, K; et al. Autosomal recessive spastic tetraplegia caused by AP4M1 and AP4B1 gene mutation: Expansion of the facial and neuroimaging features. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164:1677-1685(2014).
