AQP10
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Official Full Name
aquaporin 10
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Overview
This gene encodes a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea. -
Synonyms
AQP10; aquaporin 10; aquaporin-10; AQP 10; AQPA Human; Aquaporin10; Small intestine aquaporin; AQP-10; aquaglyceroporin-10; AQPA_HUMAN;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | AQP10-8769HCL | Recombinant Human AQP10 293 Cell Lysate | HEK293 | N/A | ||
Homo sapiens (Human) | RFL21964HF | Recombinant Full Length Human Aquaporin-10(Aqp10) Protein, His-Tagged | E.coli expression system | His | Full Length (1-301) | |
Milnesium tardigradum (Water bear) (Tardigrade) | RFL8939MF | Recombinant Full Length Milnesium Tardigradum Aquaporin-10(Aqp10) Protein, Tag-Free | E.coli expression system | Tag-Free | Full Length (1-409) |
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
AQP10 involved in several pathways and played different roles in them. We selected most pathways AQP10 participated on our site, such as Aquaporin-mediated transport, Passive transport by Aquaporins, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with AQP10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Aquaporin-mediated transport | AQP9B;AQP10A;ADCY1;GNB3B;GNB5A;GNB5;AQP1A.1;MYO5B;ADCY8 |
Passive transport by Aquaporins | AQP1A.2;AQP11;AQP10B;MIPB;AQP6;MIP;AQP3B;AQP9B;MIPA |
Transmembrane transport of small molecules | SLC12A3;FKBP1B;SLC9A6A;NIPAL3;TRPC4APA;SLC4A2A;SLC13A5A;TRPC4;SLC6A6 |
AQP10 has several biochemical functions, for example, glycerol channel activity, urea transmembrane transporter activity, water channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AQP10 itself. We selected most functions AQP10 had, and list some proteins which have the same functions with AQP10. You can find most of the proteins on our site.
Function | Related Protein |
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glycerol channel activity | AQP3;AQP9B;MIPB;AQP1A.1;AQP8A.2;AQP7;AQP8B;AQP4;AQP1A.2 |
urea transmembrane transporter activity | AQP3A;AQP10;AQP3B;AQP9A;AQP10A;AQP8A.2;AQP7;AQP3;AQP8A.1 |
water channel activity | AQP4;AQP1A.1;AQP9;AQP3B;AQP1A.2;AQP10A;AQP7;AQP8A.1;AQP10B |
AQP10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AQP10 here. Most of them are supplied by our site. Hope this information will be useful for your research of AQP10.
Research Area
Related articles
- Q&As
- Reviews
Q&As (18)
Ask a questionThe potential of targeting AQP10 for drug development is still being explored. Modulating AQP10 activity or expression may have therapeutic implications in disorders involving intestinal water and glycerol transport abnormalities. However, more research is needed to understand the feasibility and safety of targeting AQP10 for drug development.
Currently, there is limited information on specific molecules that interact with AQP10 or modulate its function. Further research is required to uncover potential regulators or interaction partners of AQP10.
Currently, there are no established clinical applications of AQP10 in diagnostics. However, future research may uncover diagnostic markers or therapeutic targets related to AQP10 in specific intestinal disorders or conditions.
The diagnostic potential of AQP10 in specific diseases is still being explored. Some studies have investigated its expression in different tissues and its association with various conditions. However, more research is needed to determine if AQP10 could serve as a reliable diagnostic marker.
Given the importance of AQP10 in water and glycerol transport in the intestine, targeting this protein may have therapeutic implications in conditions associated with altered fluid balance in the intestine. However, further studies are needed to evaluate the therapeutic potential and safety of targeting AQP10 in a clinical setting.
Aquaporin proteins share a high degree of sequence similarity, but they have distinct tissue distribution and functional properties. AQP10 differs from other aquaporins in its expression pattern, being primarily found in the intestine, and its ability to transport both water and glycerol.
Although AQP10 is primarily expressed in the intestine, some studies suggest that it may also play a role in other tissues, such as the liver and kidney. Further research is required to fully understand the physiological functions of AQP10 in different organs.
Some studies suggest that AQP10 polymorphisms may be associated with altered water and glycerol transport in the intestines, but the significance of these polymorphisms in relation to specific physiological traits or diseases requires further investigation.
There is limited information on genetic mutations in the AQP10 gene. However, some studies have identified single nucleotide polymorphisms (SNPs) in the AQP10 gene that may be associated with altered intestinal water and glycerol transport.
The potential therapeutic targeting of AQP10 is being investigated for various conditions. For example, modulating AQP10 expression or activity may have applications in managing intestinal disorders such as IBD. However, the development of specific AQP10-targeted therapies is still in its early stages and requires further study.
Currently, there is limited evidence linking specific diseases or conditions directly to mutations in the AQP10 gene. However, some studies suggest that AQP10 dysfunction may be associated with intestinal disorders such as inflammatory bowel disease (IBD) and obesity.
AQP10 research may have implications for drug delivery systems and water management technologies. Understanding the mechanisms and regulation of AQP10 could aid in the development of targeted drug delivery approaches and improved water filtration or desalination techniques. However, this application is mainly speculative at this stage and requires further investigation.
Currently, there is limited research on specific diseases or conditions directly linked to AQP10 dysfunction. However, it is believed that alterations in AQP10 expression or activity may contribute to intestinal disorders related to water and glycerol transport dysregulation.
A few studies have suggested possible roles of AQP10 in cancer progression. It has been found to be upregulated in certain cancer types, including colorectal and pancreatic cancers. However, further research is necessary to fully understand the implications of AQP10 in cancer development and progression.
Currently, there are no known animal models specifically designed to mimic AQP10-related conditions. However, researchers may use knockdown or knockout models to study the effects of AQP10 manipulation on intestinal physiology in animals.
Currently, there are no registered clinical trials specifically focused on AQP10. However, it is possible that research related to AQP10 may be included as part of broader studies on intestinal water and glycerol transport or related conditions.
As of now, there are no known specific inhibitors or activators of AQP10. Developing targeted modulators of AQP10 activity is an area of ongoing research, but significant progress in identifying such compounds has not been reported.
AQP10 is thought to play a role in both water and glycerol transport. It acts as a channel for the movement of water molecules across the cell membrane and also facilitates the transport of glycerol, a small hydrophilic molecule.
Customer Reviews (4)
Write a reviewThe exceptional performance of AQP10 protein in both ELISA and protein electron microscopy structure analysis positions it as a valuable tool in a broad range of research applications.
Researchers have successfully utilized AQP10 protein in electron microscopy studies, unraveling crucial insights into protein interactions and conformational changes.
This can involve organizing conferences, workshops, and webinars to discuss the latest advancements, share research findings, and broaden the understanding of AQP10 function.
AQP10 protein demonstrates outstanding performance in ELISA assays, making it highly recommended for researchers and scientists.
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