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Official Full Name calcium/calmodulin-dependent protein kinase II delta
Background The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
Synonyms CAMK2D; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin dependent protein kinase (CaM kinase) II delta , CAMKD; calcium/calmodulin-dependent protein kinase type II subunit delta; CaMK-II delta subunit; caMK-II subunit delta; CaM-k
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • DDK
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAMK2D-0331H Recombinant Human CAMK2D Protein, GST-Tagged Insect Cell GST
    Human CAMK2D-0332H Recombinant Human CAMK2D Protein, GST-Tagged Wheat Germ GST
    Human CAMK2D-266H Recombinant Human CAMK2D, GST-tagged, Active Sf9 Insect Cell GST
    Human CAMK2D-27263TH Recombinant Human CAMK2D N/A
    Human CAMK2D-7878HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
    Human CAMK2D-7879HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
    Mouse CAMK2D-2281M Recombinant Mouse CAMK2D Protein, DDK-tagged Insect Cell DDK
    Rat CAMK2D-1102R Recombinant Rat CAMK2D Protein Mammalian Cell His
    Chicken CAMK2D-3360C Recombinant Chicken CAMK2D Mammalian Cell His

    camk2d involved in several pathways and played different roles in them. We selected most pathways camk2d participated on our site, such as ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with camk2d were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway AKT3A; AREGB; ERBB3; NRAS; GRB2; HBEGFB; CAMK2B1; MAP2K7; NRG2; STAT5A
    Calcium signaling pathway P2RX6; CHRNA7; ADRA1BB; PRKACAB; PTGER3; PLCB4; ADRB3A; PDE1A; PPIFB; ADRB2
    cAMP signaling pathway NPY1R; ACOX1; VAV1; GRIA1; VIPR2; MC2R; PDE3B; PDE4D; AKT1; GRIA3
    HIF- signaling pathway GAPDH; NFKB1; EP300; RELA; AKT1; CUL2; MAP2K1; FLT1; MKNK2; PRKCB
    Oocyte meiosis CALML5; ITPR3; CAMK2A; MAD2L2; CALM3; PPP1CAB; ADCY1A; CUL1; BUB1; SMC1AL
    Adrenergic signaling in cardiomyocytes CAMK2B1; CALML3; RYR2; ATF4B1; CREB3L3; CACNG1; CACNA1SB; PPP1CAA; AGTR1A; PLN
    Wnt signaling pathway TCF7L2; PRICKLE1; RAC3; TBL1Y; FZD7B; WNT11; CXXC4; RAC1; RBX1; AXIN1
    Circadian entrainment GUCY1B3; CACNA1G; GRIN1; RYR3; GNG13; CALM3; GNAQ; GNAO1; MTNR1A; KCNJ9
    Long-term potentiation MAPK1; PRKACG; PPP1CA; MAP2K2; PLCB2; GRIN2B; RAP1A; MAPK3; GRM1; CALML3
    Neurotrophin signaling pathway RIPK2; HRAS; CAMK2B; SH2B1; AKT1; MAP2K1; CAMK2A; BDNF; RAC1; MAGED1
    Cholinergic synapse GNG13; PIK3R2; KCNQ2; CHRM5; KCNJ3; CREB3L1; ITPR1; PRKCA; PLCB1; KCNQ3
    Dopaminergic synapse CAMK2D; PRKCG; PPP1CA; GNB3; GNGT2; DDC; ITPR1; CALM2; MAPK13; ATF6B
    Olfactory transduction PDE2A; OR5B2; SLC8A1; OR7D2; OLFR481; OR10A5; OR1L6; OLFR154; SLC8A2; OLFR478
    Inflammatory mediator regulation of TRP channels PLCB3; PRKCA; CAMK2B; PRKCG; PRKCB; PIK3CA; CALML3; CAMK2G; ALOX12; NGF
    Insulin secretion GNAS; ATF4; PRKCB; ATP1B4; KCNMB3; INS; STX1A; INS2; CREB3L3; CREB3L2
    GnRH signaling pathway MMP14A; EGFRA; CACNA1DA; CAMK2D1; CAMK2B; MAP3K3; PLA2G4AA; ATF4; GNAQ; MAPK10
    Melanogenesis FZD9B; WNT16; WNT8A; POMC; GNA11A; FZD5; EDNRB2; WNT2B; GNAIA; WNT9A
    Oxytocin signaling pathway PPP1R12C; PLCB4; MYL9; CAMK4; CACNB3; MYLK; NFATC3; MAPK7; HRAS; CACNB4
    Glucagon signaling pathway PPP4C; PLCB3; PYGL; GNAQ; PPP3R1; PDE3B; CREB5; G6PC3; GYS1; PRKAG2
    Aldosterone synthesis and secretion HSD3B6; PRKD2; NETO2; GNA11; AGTR1A; CALML5; ATF2; CREB5; ATF1; Adcy4
    Gastric acid secretion ATP1A2; ATP1B1; ITPR1; SLC9A1; ATP4A; SST; PRKACA; CALML3; ATP1B4; Slc4a2
    Amphetamine addiction DDC; ATF2; ATF4; CREB3; CAMK4; SLC6A3; GRIN1; CREB3L1; CALM3; GRIN2A
    Tuberculosis CAMK2A; FCGR3A; HLA-DQA1; IL10RA; TLR2; NFKB1; RAB5B; HLA-DRB1; VDR; HLA-DRB4
    Proteoglycans in cancer WNT6; FZD7; PLCE1; Ctsl; ITGB1; NANOG; CBL; CAV3; PPP1R12A; SMO
    Glioma Pdgfa&Pdgfb; RAF1; IGF1R; BRAF; SHC2; KRAS; CAMK2A; TRP53; CALM4; PIK3R1

    camk2d has several biochemical functions, for example, ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by camk2d itself. We selected most functions camk2d had, and list some proteins which have the same functions with camk2d. You can find most of the proteins on our site.

    Function Related Protein
    calmodulin binding MARCKSA; MYLK2; GAP43; TRPV6; MYH4; CNN2; KCNQ1; UPF3B; PPP3R1; KCNN3
    calmodulin-dependent protein kinase activity DCX; CAMK1D; CAMK2G1; MYLK3; MAPKAPK5; DAPK1; CAMK2G; DAPK2A; MAPKAPK2B; MAPKAPK2
    ion channel binding ACTN3; PKP2; SNTA1; SUMO1; KCNQ3; KCNE2; CALM2; KCNB1; AKAP9; PKD1
    nitric-oxide synthase binding SLC14A2; NOS1AP; CD74; CAV3; ATP2B4; CAV1; DNM3; CALM1; SNTA1; SCN5A
    protein binding BRD9; SMARCAD1; EVLA; MALT1; GIPC1; ZNF599; TSSC4; SEMG2; ETS1; UBQLN4
    protein homodimerization activity CARS; CLN6; HSPB6; NR0B1; ADD2; B4GALT1; JUP; MID1; FASN; EFR3A
    protein serine/threonine kinase activity PRKACBA; CPNE3; Aatk; SLC14A2; DAPK1; PRKY; NIM1; RPS6KA1; PLK2; GRK7A
    sodium channel inhibitor activity PCSK9; SCN1B; NEDD4; SLC14A2; NEDD4L; CAMK2D
    titin binding ACTN2; ANKRD1; CALM1; ANKRD23; CALM3; OBSCN; SLC14A2; ANKRD2; TRIM63; CALM

    camk2d has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with camk2d here. Most of them are supplied by our site. Hope this information will be useful for your research of camk2d.


    Hidalgo, CG; Chung, CS; et al. The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKII delta) phosphorylates cardiac titin's spring elements. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 54:90-97(2013).
    Chen, QW; Edvinsson, L; et al. Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. BMC CELL BIOLOGY 10:-(2009).

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