CAMK2D

  • Official Full Name

    calcium/calmodulin-dependent protein kinase II delta

  • Overview

    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
  • Synonyms

    CAMK2D; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin dependent protein kinase (CaM kinase) II delta , CAMKD; calcium/calmodulin-dependent protein kinase type II subunit delta; CaMK-II delta subunit; caMK-II subunit delta; CaM-k;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • MYC
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CAMK2D-33HFL Active Recombinant Full Length Human CAMK2D Protein, N-His-tagged Sf21 His Full Length
Human CAMK2D-0331H Active Recombinant Human CAMK2D Protein, GST-Tagged Insect Cell GST
Human CAMK2D-27263TH Recombinant Human CAMK2D N/A
Human CAMK2D-0332H Recombinant Human CAMK2D Protein, GST-Tagged Wheat Germ GST
Human CAMK2D-266H Recombinant Human CAMK2D, GST-tagged, Active Sf9 Insect Cell GST
Human CAMK2D-7878HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
Human CAMK2D-7879HCL Recombinant Human CAMK2D 293 Cell Lysate HEK293 N/A
Human CAMK2D-760H Recombinant Human CAMK2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CAMK2D-9327HF Active Recombinant Full Length Human CAMK2D Protein, GST-tagged Insect (sf21) GST 1-478
Human CAMK2D-0169H Recombinant Human CAMK2D Protein (A2-I499), Tag Free Insect Cell No tag A2-I499
Human CAMK2D-2739H Recombinant Human CAMK2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CAMK2D-0170H Recombinant Human CAMK2D Protein (A2-I499), GST tagged Insect Cell GST A2-I499
Human CAMK2D-2785HF Recombinant Full Length Human CAMK2D Protein, GST-tagged In Vitro Cell Free System GST 478 amino acids
Mouse CAMK2D-2281M Recombinant Mouse CAMK2D Protein, DDK-tagged Insect Cell DDK
Mouse Camk2d-030M Recombinant Mouse Camk2d Protein, DDK-tagged Insect Cell DDK
Mouse Camk2d-031M Recombinant Mouse Camk2d Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CAMK2D-1102R Recombinant Rat CAMK2D Protein Mammalian Cell His
Rat CAMK2D-766R Recombinant Rat CAMK2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CAMK2D-766R-B Recombinant Rat CAMK2D Protein Pre-coupled Magnetic Beads HEK293
Chicken CAMK2D-3360C Recombinant Chicken CAMK2D Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CAMK2D involved in several pathways and played different roles in them. We selected most pathways CAMK2D participated on our site, such as ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAMK2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayPTK2AB;TGFA;GSK3AA;MAPK9;PLCG1;RPS6KB1;ERBB4;MYCB;PTK2
Calcium signaling pathwayPHKA1;ADRa1A;AGTR1;ATP2A3;TACR1A;BDKRB1;TRHRB;Adcy4;PLCD3
cAMP signaling pathwayGPR81;RHOA;FXYD2;PDE4C;NFKB1;VAV3;AMH;PRKACA;PTGER2
HIF- signaling pathwayANGPT2;STAT3;PIK3CB;TFRC;NOS2;VHL;GAPDH;PIK3R1;MAP2K2
Oocyte meiosisCDC27;SMC1AL;CCNE1;PRKACBB;CALM2;Adcy4;CAMK2G1;CUL1B;IGF1R
Adrenergic signaling in cardiomyocytesCALM1;ATP2B3B;GNAI1;PPP2R5B;ADCY1;ADRa1A;BCL2A;CALML5;GNAI3
Wnt signaling pathwayBAMBIA;RHOAD;WNT6;FZD7;BAMBI;RAC1;NLK;LEF1;CER1
Circadian entrainmentGNG11;Adcy4;PLCB3;GNAQ;GRIA2;ADCYAP1R1;PER2;GNG10;GNG3
Long-term potentiationPRKCA;CAMK2D;RAF1;CAMK2B;PPP3CC;GRIN1;MAP2K2;GRIN2C;CAMK2A
Neurotrophin signaling pathwayMAPK1;PIK3R3;NFKBIE;CALML5;BAD;NTRK3;MAP3K3;ABL1;SHC4
Cholinergic synapsePIK3CB;CAMK2G;GNG5;KCNJ12;GNAI3;PRKACB;KCNQ5;CHRM4;CHRM1
Dopaminergic synapseKCNJ3;GNG4;GRIN2B;MAPK11;PRKACG;KIF5C;PPP3CB;MAOB;PRKACB
Olfactory transductionOR2K2;OR10A4;OR3A2;OLFR477;OR51B4;OR4D6;GUCY2E;OR8K5;CAMK2G
Inflammatory mediator regulation of TRP channelsMAPK9;PRKCB;PIK3CB;BDKRB2;CYP2C55;MAPK12;CAMK2A;TRPV2;MAP2K3
Insulin secretionCREB5;INS1;ATP1A2;CAMK2B;CREB3L3;PRKCB;ATP1A4;KCNN4;CAMK2G
GnRH signaling pathwayPLCB2;CAMK2D;PLD2;CAMK2G;SRC;MAP3K2;MAPK8A;CACNA1SA;GNAQ
MelanogenesisWNT11B;POMCA;FZD10;GNAIA;KIT;EDNRBA;WNT2BA;a;WNT5A
Oxytocin signaling pathwayCACNG8;PRKAA2;CCND1;MYL6;RCAN1;CALML5;CAMK2A;PPP3CC;CAMKK2
Aldosterone synthesis and secretionDDX1;ADCY3;AKR1C1;CYP11A1;PRKACG;PLCB3;CREB5;CALM1;HSD3B5
Gastric acid secretionPRKCG;GNAI1;KCNJ1;GNAI2;ATP4B;GNAS;SLC26A7;SSTR2;KCNK2
TuberculosisITGB2L;HLA-DMA;Itgam&Itgb2;HLA-DQB1;cgr2b;HLA-DOA;HLA-DRB5;Pla2r1;IFNA8
Proteoglycans in cancerSMO;MAP2K1;PTPN11;WNT3;MSN;CCND1;PTK2;CAMK2A;WNT2B
GliomaIGF1;AKT1;PIK3CA;PIK3CB;SHC2;PIK3R3;CALML5;CALM3;RAF1

CAMK2D has several biochemical functions, for example, ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAMK2D itself. We selected most functions CAMK2D had, and list some proteins which have the same functions with CAMK2D. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCSF1R;TOR1A;KIF1B;PDIK1L;AK8;ABCC2;AKT2;AACS;ERN2
calmodulin bindingCALD1B;KCNQ1;TRPV5;CNN1A;ATP2B1;TRPV1;DAPK1;EPB41B;ENKUR
calmodulin-dependent protein kinase activityMAPKAPK2A;CAMK1D;MYLK3;CAMKK2;MAPKAPK2;DAPK2A;CAMKK1;MYLK2;CAMK2D2
ion channel bindingKCNE4;FAM115A;CALM1;AASS;HOMER1;SLC8A1;FGF12;KCNB1;ACTN1
nitric-oxide synthase bindingNOS1AP;CAV1;DNM3;SCN5A;SLC14A2;ACTB;DNM2;CDH2;CAMK2D
protein bindingNRG1;PSMB5;RAPGEF4;NDUFB10;LRRC4;CTAG1A;TJAP1;OSTC;RBM10
protein homodimerization activityATP2A1;TERF2;PDGFA;ADD2;GSS;PRMT8;DSCAML1;TIMM9;ACTN4
protein serine/threonine kinase activityMAP3K13;ROCK2A;MAST2;ZNF143B;MARK1;CDK16;NIM1;PSKH2;LMTK3
sodium channel inhibitor activityNEDD4L;SLC14A2;NEDD4;PCSK9;SCN1B;CAMK2D
titin bindingCALM3;ANKRD2;TCAP;ANKRD23;ACTN2;TRIM63;OBSCN;ANKRD1B;CALM

CAMK2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAMK2D here. Most of them are supplied by our site. Hope this information will be useful for your research of CAMK2D.

SCN5A; TNPO2; DNAL4

Research Area

Related articles

Hidalgo, CG; Chung, CS; et al. The multifunctional Ca2+/calmodulin-dependent protein kinase II delta (CaMKII delta) phosphorylates cardiac titin's spring elements. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 54:90-97(2013).
Chen, QW; Edvinsson, L; et al. Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. BMC CELL BIOLOGY 10:-(2009).
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