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SELP

  • Official Full Name

    selectin P (granule membrane protein 140kDa, antigen CD62)

  • Overview

    This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
  • Synonyms

    SELP; selectin P (granule membrane protein 140kDa, antigen CD62); GRMP, selectin P (granule membrane protein 140kD, antigen CD62); P-selectin; CD62; CD62P; GMP140; PADGEM; PSEL; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein; GRMP; LECAM3; FLJ45155;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Ovis aries (Sheep)
  • Rabbit
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus
  • Zebrafish
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • Mammalian Cell
  • Mammalian cells
  • Avi
  • His
  • C
  • 6His
  • hFc
  • Fc
  • Fc|His
  • Myc
  • His (Fc)
  • His\Avi
  • His|T7
  • human|IgG1|Fc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SELP-473H Active Recombinant Human SELP protein, hFc-tagged HEK293 hFc Met1-Ala771
Human SELP-457H Active Recombinant Human SELP, Fc Chimera HEK293 Fc/His
Human SELP-2585H Recombinant Human SELP protein, His & T7-tagged E.coli His/T7 Arg198~Asn432 (Accession # P16109)
Human SELP-458H Recombinant Human SELP HEK293 N/A
Human SELP-2584H Recombinant Human SELP protein, His-tagged E.coli His Lys58~Glu195 (Accession # P16109)
Human SELP-208H Recombinant Human SELP protein, Fc-tagged HEK293 human/IgG1/Fc Trp42-Ala771
Human SELP-8327H Recombinant Human SELP CHO N/A
Human SELP-27886TH Recombinant Human SELP N/A
Human SELP-1674H Recombinant Human SELP Mammalian cells N/A
Human SELP-282H Recombinant Human selectin P, His-tagged E.coli His
Human SELP-474H Recombinant Human SELP protein, His-tagged HEK293 His Trp42-Ala771
Human SELP-1598HCL Recombinant Human SELP cell lysate Human Cell N/A
Human SELP-0648H Recombinant Human SELP protein, Fc-tagged HEK293 Fc Trp42-Ala771
Human SELP-1528H Recombinant Human SELP protein, hFc-Myc-tagged HEK293 hFc-Myc 42-771aa
Human SELP-404H Recombinant Human SELP Protein, Fc-tagged HEK293 Fc 830
Human SELP-3078H Recombinant Human SELP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SELP-2185H Recombinant Human SELP protein, His-tagged HEK293 His Met1-Ala771
Human SELP-4478H-B Recombinant Human SELP Protein Pre-coupled Magnetic Beads HEK293
Human SELP-387H Recombinant Human SELP Protein (Trp42-Aal771), C-hFc-tagged HEK293 C-hFc Trp42-Aal771
Human SELP-151H Recombinant Human SELP Protein, His-tagged Human cells His
Human SELP-6261H Recombinant Human SELP Protein (Lys58-Glu195), His tagged E.coli His Lys58-Glu195
Human SELP-3364H Recombinant Human SELP protein, His and hFc-tagged HEK293 His and hFc Lys58~Glu195
Human SELP-5085H Recombinant Human SELP Protein (Met1-Ala771), C-His tagged Mammalian cells C-His Met1-Ala771
Human SELP-403H Recombinant Human SELP Protein, His-tagged HEK293 His 830
Human SELP-4478H Recombinant Human SELP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SELP-598H Recombinant Human SELP Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SELP-109HB Recombinant Human SELP protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Trp 42-Ala 771
Human SELP-109H Recombinant Human SELP protein, His-Avi-tagged HEK293 His-Avi It contains Trp 42 - Ala 771.
Mouse SELP-905M Active Recombinant Mouse SELP protein, hFc-tagged HEK293 hFc Met1-Ala709
Mouse Selp-2586M Recombinant Mouse Selp protein, His-tagged E.coli His Val58~Ala259 (Accession # Q01102)
Mouse SELP-305M Active Recombinant Mouse SELP protein, His-tagged HEK293 His Met1-Ala709
Mouse Selp-8340M Recombinant Mouse Selp Mammalian cells N/A
Mouse Selp-534M Recombinant Mouse Selp, Fc-tagged Human Cell Fc Met1-Ala709
Mouse SELP-972MCL Recombinant Mouse SELP cell lysate Human Cell N/A
Mouse Selp-5757M Recombinant Mouse Selp Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SELP-306M Recombinant Mouse SELP(Trp42­Ala709) Protein, C-Avi-6*His-tagged, Biotinylated HEK293 Avi-His
Mouse Selp-05M Recombinant Mouse Selp Protein, C-Avi-6His tagged, Biotinylated Human Cell C-Avi-6His Trp42-­Ala709
Mouse SELP-177M Recombinant Mouse SELP Protein, His\Avi-tagged Human Cell His\Avi
Mouse Selp-10612M-B Recombinant Mouse Selp Protein Pre-coupled Magnetic Beads HEK293
Mouse Selp-10612M Recombinant Mouse Selp Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SELP-1114R Active Recombinant Rat SELP protein(Met1-Gln700), hFc-tagged HEK293 C-hFc Met1-Gln700
Rat Selp-2587R Recombinant Rat Selp protein, His-tagged E.coli His Ala58~Cys158 (Accession # P98106)
Rat Selp-563R Recombinant Rat Selp, His-tagged Human Cell His Met1-Gln700
Rat SELP-5310R Recombinant Rat SELP Protein Mammalian Cell His
Rat SELP-001RCL Recombinant Rat SELP cell lysate Human Cell N/A
Rat SELP-4969R-B Recombinant Rat SELP Protein Pre-coupled Magnetic Beads HEK293
Rat SELP-4969R Recombinant Rat SELP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rabbit SELP-1223R Recombinant Rabbit SELP Protein, His-tagged E.coli N-His Val39-Glu195
Bos taurus (Bovine) RFL32002BF Recombinant Full Length Bovine P-Selectin(Selp) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (42-646)
Cynomolgus Monkey SELP-192C Recombinant Cynomolgus SELP, His-tagged Human Cell His Met1-Ala771
Cynomolgus Monkey SELP-001CCL Recombinant Cynomolgus SELP cell lysate Human Cell N/A
Mus musculus (Mouse) RFL7276MF Recombinant Full Length Mouse P-Selectin(Selp) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (42-768)
Ovis aries (Sheep) RFL20752OF Recombinant Full Length Sheep P-Selectin(Selp) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-769)
Rattus norvegicus (Rat) RFL29916RF Recombinant Full Length Rat P-Selectin(Selp) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (42-768)
Rhesus SELP-530R Recombinant Rhesus SELP Protein, Fc-tagged HEK293 Fc Met1-Ala771
Rhesus SELP-531R Recombinant Rhesus SELP protein, His-tagged HEK293 His Met1-Ala771
Zebrafish SELP-8050Z Recombinant Zebrafish SELP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SELP Related Research Area

SELP involved in several pathways and played different roles in them. We selected most pathways SELP participated on our site, such as Cell adhesion molecules (CAMs), Malaria, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SELP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)CLDNA;CLDN5B;NRXN1;CLDNC;NFASCA;ITGAM;NCAM2;ITGB1A;CD6
MalariaKLRC4-KLRK1;CD81;THBS4;IL12A;HBA-A2;IL1B;SDC2;GYPB;KLRB1
Staphylococcus aureus infectionC5AR1;FCGR4;HLA-DQB1;MBL2;PLG;HLA-DRA;SELPLG;DSG1C;C3

SELP has several biochemical functions, for example, calcium-dependent protein binding, fucose binding, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SELP itself. We selected most functions SELP had, and list some proteins which have the same functions with SELP. You can find most of the proteins on our site.

Function Related Protein
calcium-dependent protein bindingS100PBP;A2M;S100P;MYO1D;TSG101;S100A6;C9orf9;KCNIP3;MBL2
fucose bindingFUOM;FUCA1;FUCA2;SELP
glycoprotein bindingSerpina1c;DNAJA2;CALR;HSPA5;FOXRED2;B2M;CNTN1;FYN;LRRK2
glycosphingolipid bindingLAMA1;SELP;SELL;Il2;LYN;LAMB1;LAMC1;Cel
heparin bindingADAMTS3;ECM2;PCOLCE2;ABP1;APOA5;CCL15;HDGF;PGF;Itgam&Itgb2
lipopolysaccharide bindingTREM2;HMGB1;SCARB1;CD6;TLR2;TLR4;RNASE7;BPIFC;SPON2
oligosaccharide bindingCHID1;SELP;DCBLD1;RS1A;SELE;LOXL2
protein bindingSH3PXD2B;CCDC88A;UGGT2;CCDC6;CCT6A;IL11;HTN1;TMEM31;SCMH1
sialic acid bindingST8SIA2;AGRN;ST8SIA3;SELP;FCN1;ADIPOQ;L1CAM;SELE;Siglece

SELP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SELP here. Most of them are supplied by our site. Hope this information will be useful for your research of SELP.

SELPLG

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