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Official Full Name deltex homolog 1 (Drosophila)
Background Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
Synonyms DTX1; deltex homolog 1 (Drosophila); protein deltex-1; hDx 1; Deltex protein 1; Deltex-1; Deltex1; FXI-T1; Fxit 1; Fxit1; mDTX1; hDTX1; OTTHUMP00000241684; hDx-1
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DTX1-1842H Recombinant Human DTX1 protein, His & T7-tagged E.coli His/T7
    Human DTX1-2905H Recombinant Human DTX1 Protein, GST-tagged Wheat Germ GST
    Mouse DTX1-4856M Recombinant Mouse DTX1 Protein Mammalian Cell His
    Zebrafish DTX1-6779Z Recombinant Zebrafish DTX1 Mammalian Cell His

    dtx1 involved in several pathways and played different roles in them. We selected most pathways dtx1 participated on our site, such as Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with dtx1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Notch signaling pathway DLA; HDAC1; NUMB; CTBP2; DLC; PSENEN; NCOR2; HER6; TUBB3; DLK1

    dtx1 has several biochemical functions, for example, Notch binding, SH3 domain binding, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by dtx1 itself. We selected most functions dtx1 had, and list some proteins which have the same functions with dtx1. You can find most of the proteins on our site.

    Function Related Protein
    Notch binding DLL1; DLL3; DNER; JAG2B; NCOR2; NOV; SNW1; CHAC1; AAK1; JAG2
    SH3 domain binding UVRAG; CTTNBP2; BCAR1; NCKIPSD; PTPN22; ARHGAP27; SH3BP2; GJA1; FMN1; WAS
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity TRIM71; TRIM41; MUL1A; UBR1; UBE2IB; RNF169; MARCH4; RNF144AB; HERC2; RNF187
    coenzyme F420-0 gamma-glutamyl ligase activity MARCH4; MGRN1A; MARCH6; SIAH1A; RC3H2; NEURL1B; UBR1; HERC2; SIAH2L; TRIM41
    coenzyme F420-2 alpha-glutamyl ligase activity HECW2; G2E3; TMEM129; SIAH1A; RNF144AB; RNF169; TRIM71; ARIH1L; RNF180; SHRPRBCK1R
    ligase activity TRIM33; MARCH11; AMFR; RNF168; TRIP12; UBR2; UBR5; PELI3; GLULB; DTX3L
    metal ion binding ADH8B; SUMF2; PPM1DA; NME7; CRACR2B; SMYD1; ATP13A4; FBXL19; GFI1AB; SH3RF3
    protein binding Car4; ORC3L; PKN3; HOPX; UFC1; NFKBIB; RQCD1; TSPAN2; MEIOB; TPSB2
    protein-glutamic acid ligase activity HERC2; RNF180; UBR1; TMEM129; UBE2IB; LTN1; HECW2; MGRN1A; TRIM71; ARIH1L
    protein-glycine ligase activity RFWD2; UBE2IB; TMEM129; RNF187; RNF149; DTX1; MYLIPB; TRIM50; ZNRF2B; ARIH1L
    protein-glycine ligase activity, elongating ARIH1L; TRIM50; NEURL3; MARCH9; RAG1; MARCH6; MYLIPB; ZNRF2B; UBR1; MARCH5L
    protein-glycine ligase activity, initiating SHRPRBCK1R; MARCH6; UBE2IB; RNF187; MYLIPA; MARCH9; RFWD2; MARCH5L; RNF144AA; TRIM71
    ribosomal S6-glutamic acid ligase activity MARCH9; RFWD2; MGRN1A; RNF144AA; UBE2IB; TRIM41; TRIM71; RAG1; UBR1; MARCH6
    tubulin-glutamic acid ligase activity RNF180; MYLIPB; UBE2IB; DTX1; MARCH4; NEURL1B; RNF144AA; MARCH11; LTN1; SIAH2L
    tubulin-glycine ligase activity SHRPRBCK1R; FLR; ARIH1L; TMEM129; MYLIPB; ZNRF3; TRIM41; HECW2; UBE2IA; MARCH9
    ubiquitin protein ligase binding GPI1; IKBKG; ERLIN2; MAP1LC3B; UBE2V2; CDC34A; UBE2W; KDM4A; TRIOBP; RPA3
    zinc ion binding PIAS1; MARCH2; MT1X; RNF128A; BTY; PARK2; LTA4H; CPO; Car8; BRF1B

    dtx1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with dtx1 here. Most of them are supplied by our site. Hope this information will be useful for your research of dtx1.

    Aste-Amezaga, M; Zhang, NY; et al. Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors. PLOS ONE 5:-(2010).
    Laycock, MV; Jellett, JF; et al. First report of a new rapid assay for diarrhetic shellfish poisoning toxins. HARMFUL ALGAE 5:74-78(2006).

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