FAM84B

  • Official Full Name

    family with sequence similarity 84, member B
  • Overview

    FAM84B belongs to the FAM84 family. It is expressed in esophageal squamous cell carcinomas.
  • Synonyms

    FAM84B;family with sequence similarity 84, member B;protein FAM84B;BCMP101;breast cancer membrane associated protein 101;neurological/sensory 2;NSE2;BF642811;D330050I23Rik;Breast cancer membrane protein 101;Breast cancer membrane-associated protein 101;FA84B_HUMAN;Family with sequence similarity 84 member B;OTTHUMP00000228215;Protein NSE2;RGD1562236
Cat.# Product name Source (Host) Species Tag Protein Length Price
FAM84B-12729H Recombinant Human FAM84B, His-tagged E.coli Human His 1-310a.a.
FAM84B-2442H Recombinant human FAM84B, His-tagged E.coli Human His
FAM84B-3809H Recombinant Human FAM84B Protein, GST-tagged Wheat Germ Human GST
FAM84B-3992Z Recombinant Zebrafish FAM84B Mammalian Cells Zebrafish His
FAM84B-6342HCL Recombinant Human FAM84B 293 Cell Lysate HEK293 Human Non
FAM84B-4648HF Recombinant Full Length Human FAM84B Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 310 amino acids

    Involved Pathway

    FAM84B involved in several pathways and played different roles in them. We selected most pathways FAM84B participated on our site, such as Aflatoxin B1 metabolism,Aflatoxin activation and detoxification,Benzo(a)pyrene metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAM84B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Aflatoxin B1 metabolism CYP1A2,CYP3A4,PRKRA,CYP2A13
    Cytochrome P450 - arranged by substrate type CYP27A1,FDX1L,CYP4A11,CYP2B6,CYP17A1,CYP4F12,CYP3A7,POMCB,CYP7A1,CYP2U1
    Benzo(a)pyrene metabolism CYP1A1,CYP1B1,AKR1C2,CYP3A4,AKR1C4,AKR1A1
    Bile secretion AQP8,SLC51A,ABCB11,PRKACB,AQP9,ADCY9,CYP3A4,ABCC3,NR1H4,LDLR
    Biological oxidations SLC35B3,ADH5,CYP2W1,CYP2AD3,ACSM1,UGT1B7,UGT1B4,CYP4T8,SLC35B2,CYP2C9
    Chemical carcinogenesis GSTT2,ADH1A,MGST3,GSTT2B,GSTK1,Nat3,CYP2A6,GSTT1,CYP2C54,UGT1A3
    Aflatoxin activation and detoxification CYP2A13,CYP1A2,ACY3,CYP3C1,PRKRA,DPEP2,ACY3.2,CYP3A5,GGT6,CYP3C4

    Protein Function

    FAM84B has several biochemical functions, for example, aromatase activity,caffeine oxidase activity,enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM84B itself. We selected most functions FAM84B had, and list some proteins which have the same functions with FAM84B. You can find most of the proteins on our site.

    Function Related Protein
    steroid binding CYP21A2,PGR,ESRRG,UGT1A1,NR3C1,HSD11B2,PAQR7,HSD3B5,PAQR7A,CYP3A4
    monooxygenase activity FOXRED2,CYP3A25,FMO2,CYP1A1,CYP2AD6,CYP8B1,BCO1,MICAL2B,CYP3A7,CYP4F22
    vitamin D3 25-hydroxylase activity CYP3A4,CYP2R1,CYP27A1
    testosterone 6-beta-hydroxylase activity CYP3A41A,CYP3A41B,CYP3A4,CYP3A25
    enzyme binding RYR2,TNKS2,KAT8,PPP3CA,HDAC1,FOXO4,PEX7,SLPI,SCNM1,THRB
    steroid hydroxylase activity CYP2A13,CYP2AD3,CYP2C70,CYP2AA2,CYP2J2,CYP2K22,CYP3A4,CYP2C54,CYP2J5,CYP2P8
    quinine 3-monooxygenase activity CYP3A4
    vitamin D 24-hydroxylase activity CYP1A1,CYP3A4
    oxygen binding CYP26A1,CYP2P8,CYP2C9,CYP2C50,CYP2W1,HBAA,CYP2D9,CYP2AA9,BA1,CYP2C8

    Interacting Protein

    FAM84B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM84B here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM84B.

    UROD;CHEK2;RAD51;XRCC3;BAG4;PTPN1;FGFR4;NOTCH2;SMAD4;PALB2;ESR2

    Resources

    References

    • Du, MJ; Yuan, TZ; et al. Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. HUMAN MOLECULAR GENETICS 24:154-166(2015).
    • Ji, W; Bian, ZH; et al. Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells. INTERNATIONAL JOURNAL OF CANCER 134:1279-1288(2014).

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