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Official Full Name family with sequence similarity 84, member B
Background FAM84B belongs to the FAM84 family. It is expressed in esophageal squamous cell carcinomas.
Synonyms FAM84B; family with sequence similarity 84, member B; protein FAM84B; BCMP101; breast cancer membrane associated protein 101; neurological/sensory 2; NSE2; BF642811; D330050I23Rik; Breast cancer membrane protein 101; Breast cancer membrane-associated protein 101; FA84B_HUMAN; Family with sequence similarity 84 member B; OTTHUMP00000228215; Protein NSE2; RGD1562236
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FAM84B-12729H Recombinant Human FAM84B, His-tagged E.coli His
    Human FAM84B-2442H Recombinant human FAM84B, His-tagged E.coli His
    Human FAM84B-3809H Recombinant Human FAM84B Protein, GST-tagged Wheat Germ GST
    Human FAM84B-6342HCL Recombinant Human FAM84B 293 Cell Lysate HEK293 N/A
    Zebrafish FAM84B-3992Z Recombinant Zebrafish FAM84B Mammalian Cell His

    fam84b involved in several pathways and played different roles in them. We selected most pathways fam84b participated on our site, such as Aflatoxin B1 metabolism, Aflatoxin activation and detoxification, Benzo(a)pyrene metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with fam84b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Aflatoxin B1 metabolism CYP3A4; CYP2A13; FAM84B; CYP1A2; PRKRA
    Aflatoxin activation and detoxification CYP3A4; CYP1A2; CYP3C4; ACY3; GGTLC1; ACY3.2; FAM84B; DPEP1; GGT6; CYP2A13
    Benzo(a)pyrene metabolism CYP1B1; CYP3A4; CYP1A1; AKR1C2; FAM84B; AKR1C4; AKR1A1
    Bile secretion ADCY6; Slc4a2; SLC10A2; ATP1B1; Abcb1b; FAM84B; CA2; SLC22A7; SLCO1A2; ATP1A3
    Biological oxidations ADH4; ACY3.2; CYP2C19; CYP1A1; SLC26A1; CYP2R1; GSTO2; SULT1B1; CYP3A5; DPEP1
    Chemical carcinogenesis GSTM5; GSTT1; CYP2C39; GSTO2; CYP1B1; ADH1; NAT2; CYP3A7-CYP3AP1; GSTT2; ADH7
    Codeine and morphine metabolism CYP2D6; SLCO1B1; ABCC2; CYP3A4; FAM84B
    Cytochrome P450 - arranged by substrate type CYP46A1; CYP2K6; CYP7A1; CYP4A11; CYP2W1; CYP2C9; CYP3A7-CYP3AP1; CYP3A5; CYP51A1; CYP4F22

    fam84b has several biochemical functions, for example, albendazole monooxygenase activity, aromatase activity, caffeine oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by fam84b itself. We selected most functions fam84b had, and list some proteins which have the same functions with fam84b. You can find most of the proteins on our site.

    Function Related Protein
    albendazole monooxygenase activity CYP3A4; FAM84B
    aromatase activity CYP3A7; CYP1A4; CYP1A1; CYP2H1; CYP4Z1; CYP2C55; CYP2D26; CYP2C9; CYP2J2; CYP4A12A
    caffeine oxidase activity FAM84B; CYP2C9; CYP2C38; CYP1A2; CYP2C39; CYP3A4
    enzyme binding PPP3CB; TBP; KDM1A; TULP3; CASC3; LDB2; PEX7; CTNNB1; RARA; Ar
    heme binding CYP7A1A; CYP2C37; NGB; HBAA1; CYP2C8; CYP11B1; HBB-BH1; CYP2F2; CYP46A1; HBG2
    iron ion binding AOX3; CYP4A10; POR; CYP2D9; CYP26B1; BBOX1; HBD; HBBE3; CYP4A14; CYP26C1
    monooxygenase activity TH2; CYP2P7; CYP4T8; CYP27C1; CYP2N13; CYP46A1.2; CYP2X10.2; CYP4V2; CYP1D1; CYP2AA1
    oxidoreductase activity CYP2AD6; CYP2D9; SCCPDHA; PHF2; CYP2X7; MICAL2B; HMGCRA; PYROXD1; AKR1A1A; CYP4A14
    oxygen binding CYP2AD6; CYP2AD3; CYP2AA12; CYP3A4; CYGB1; HBA-X; CYP2AA3; CYP2X9; HBAE1; CYP2J2
    quinine 3-monooxygenase activity FAM84B; CYP3A4
    steroid binding PGR; PGRMC1; PAQR5A; SERPINA6; ESRRA; HSD3B5; CYP3A4; PAQR5B; HSD17B10; NR3C2
    steroid hydroxylase activity CYP2C19; CYP2A6; CYP2K19; BRSK2; CYP2D10; CYP2AA8; CYP2F1; CYP2V1; CYP46A1.2; CYP2Y3
    taurochenodeoxycholate 6alpha-hydroxylase activity CYP3A4; FAM84B
    testosterone 6-beta-hydroxylase activity CYP3A41B; CYP3A4; CYP3A25; CYP3A41A; FAM84B
    vitamin D 24-hydroxylase activity CYP1A1; FAM84B; CYP3A4
    vitamin D3 25-hydroxylase activity CYP27A1; CYP2R1; CYP3A4; FAM84B

    fam84b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fam84b here. Most of them are supplied by our site. Hope this information will be useful for your research of fam84b.


    Du, MJ; Yuan, TZ; et al. Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. HUMAN MOLECULAR GENETICS 24:154-166(2015).
    Ji, W; Bian, ZH; et al. Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells. INTERNATIONAL JOURNAL OF CANCER 134:1279-1288(2014).

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