KRT12
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Official Full Name
keratin 12 -
Overview
Belongs to the intermediate filament family. May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity. -
Synonyms
KRT12;keratin 12;K12;keratin, type I cytoskeletal 12;CK-12;keratin-12;cytokeratin-12;Meesmann corneal dystrophy;OTTHUMP00000164524;Keratin K12
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- DDK
- Myc
- Avi
- Fc
Involved Pathway
KRT12 involved in several pathways and played different roles in them. We selected most pathways KRT12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KRT12 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT12 itself. We selected most functions KRT12 had, and list some proteins which have the same functions with KRT12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | ASPH,SEMG2,SNTB1,EVPLA,CLDN7B,COPB2,CLDN5A,DESMA,ISCA2,KRT6C |
Interacting Protein
KRT12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT12 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT12.
Resources
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References
- Vera-Sirera, B; Forner-Navarro, L; et al. NCAM (CD56) Expression in keratin-producing odontogenic cysts: aberrant expression in KCOT. HEAD & FACE MEDICINE 11:-(2015).
- Alomari, AK; Glusac, EJ; et al. p40 is a more specific marker than p63 for cutaneous poorly differentiated squamous cell carcinoma. JOURNAL OF CUTANEOUS PATHOLOGY 41:839-845(2014).
