KRT17

  • Official Full Name

    Keratin 17

  • Background

    This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychiacongenita and steatocystoma multiplex.
  • Synonyms

    PC; K17; PC2; PCHC1; KRT17; keratin, type I cytoskeletal 17; 39.1; CK-17; keratin-17; cytokeratin-17; OTTHUMP00000164770;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Bovine
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • His|S
    • His|SUMO
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Price
    Human KRT17-483H Recombinant Human keratin 17, His-tagged E.coli His
    Human KRT17-1843H Recombinant Human KRT17 protein, His & S-tagged E.coli His/S
    Human KRT17-5084H Recombinant Human KRT17, His-tagged E.coli His
    Human KRT17-017H Recombinant human KRT17, GST-tagged Wheat Germ GST
    Human KRT17-953HCL Recombinant Human KRT17 cell lysate N/A
    Human KRT17-735HF Recombinant Full Length Human KRT17 Protein, GST-tagged In Vitro Cell Free System GST
    Human KRT17-2412H Recombinant Human KRT17 Protein (Ile252-Ala393), His tagged E.coli His
    Human KRT17-4392H Recombinant Human KRT17 Protein (Ile252-Ala393), N-His tagged E.coli N-His
    Mouse KRT17-8820M Recombinant Mouse KRT17 Protein Mammalian Cell His
    Mouse KRT17-4913M Recombinant Mouse KRT17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse KRT17-4913M-B Recombinant Mouse KRT17 Protein Pre-coupled Magnetic Beads HEK293
    Rat KRT17-3314R Recombinant Rat KRT17 Protein Mammalian Cell His
    Rat Krt17-12R Recombinant Rat Krt17 protein, His-tagged E.coli His
    Rat KRT17-2970R Recombinant Rat KRT17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat KRT17-2970R-B Recombinant Rat KRT17 Protein Pre-coupled Magnetic Beads HEK293
    Bovine KRT17-611B Recombinant Bovine KRT17 Protein (1-441 aa), His-SUMO-tagged E.coli His/SUMO
    Zebrafish KRT17-5398Z Recombinant Zebrafish KRT17 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    KRT17 involved in several pathways and played different roles in them. We selected most pathways KRT17 participated on our site, such as EGFR1 Signaling Pathway, Glucocorticoid receptor regulatory network, which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    EGFR1 Signaling PathwayPLSCR1;RGS16;ZNF259;PTPN12;PTK6;RALBP1;USP6NL;SH2D3C;KLF11
    Glucocorticoid receptor regulatory networkSMARCD1;BGLAP;EGR1;CSN2;SMARCA4;KRT17;NR1I3;SMARCC2;KRT14

    KRT17 has several biochemical functions, for example, MHC class II protein binding, MHC class II receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT17 itself. We selected most functions KRT17 had, and list some proteins which have the same functions with KRT17. You can find most of the proteins on our site.

    Function Related Protein
    MHC class II protein bindingCD4;LAG3;KRT17;MARCH8;CD74A;CD74;CD74B
    MHC class II receptor activityHLA-DQA2;HLA-DOB;HLA-DRA;HLA-DQA1;HLA-DRB4;HLA-DQB1;HLA-DRB1;HLA-DPA1;HLA-DOA
    protein bindingGLA;ATRNL1;TMPO;GLYCTK;RPN1;NSF;ARMCX5;SGOL1;IL12A
    structural constituent of cytoskeletonTUBB1;NEFH;TUBA8L4;ANK1;ACTA1;ACTR2;TUBA1A;TUBA1L;ACTG1

    KRT17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT17 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT17.

    CCDC85B; USP1; UCHL1; KDM1A; SNAPIN; KRT6A; APC; ZDHHC17; midostaurin; EGFR; CFTR; GRB2; YWHAZ; NETO2; GABARAPL1

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