KRT17

  • Official Full Name

    Keratin 17

  • Overview

    This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychiacongenita and steatocystoma multiplex.
  • Synonyms

    PC; K17; PC2; PCHC1; KRT17; keratin, type I cytoskeletal 17; 39.1; CK-17; keratin-17; cytokeratin-17; OTTHUMP00000164770;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His|S
  • His|SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KRT17-483H Recombinant Human keratin 17, His-tagged E.coli His
Human KRT17-1843H Recombinant Human KRT17 protein, His & S-tagged E.coli His/S Ile252~Ala393 (Accession # Q04695)
Human KRT17-5084H Recombinant Human KRT17, His-tagged E.coli His
Human KRT17-017H Recombinant human KRT17, GST-tagged Wheat Germ GST
Human KRT17-953HCL Recombinant Human KRT17 cell lysate N/A
Human KRT17-735HF Recombinant Full Length Human KRT17 Protein, GST-tagged In Vitro Cell Free System GST 432 amino acids
Human KRT17-2826H Recombinant Human KRT17 protein(71-400 aa), C-His-tagged E.coli C-His 71-400 aa
Human KRT17-4392H Recombinant Human KRT17 Protein (Ile252-Ala393), N-His tagged E.coli N-His Ile252-Ala393
Mouse KRT17-8820M Recombinant Mouse KRT17 Protein Mammalian Cell His
Mouse KRT17-4913M Recombinant Mouse KRT17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse KRT17-4913M-B Recombinant Mouse KRT17 Protein Pre-coupled Magnetic Beads HEK293
Rat KRT17-3314R Recombinant Rat KRT17 Protein Mammalian Cell His
Rat Krt17-12R Recombinant Rat Krt17 protein, His-tagged E.coli His
Rat KRT17-2970R Recombinant Rat KRT17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KRT17-2970R-B Recombinant Rat KRT17 Protein Pre-coupled Magnetic Beads HEK293
Bovine KRT17-611B Recombinant Bovine KRT17 Protein (1-441 aa), His-SUMO-tagged E.coli His/SUMO 1-441 aa
Zebrafish KRT17-5398Z Recombinant Zebrafish KRT17 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

KRT17 involved in several pathways and played different roles in them. We selected most pathways KRT17 participated on our site, such as EGFR1 Signaling Pathway, Glucocorticoid receptor regulatory network, which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EGFR1 Signaling PathwayZNF259;TNIP1;DNM1;USP6NL;KRT8;ELF3;JUND;AP2A1;PTPN12
Glucocorticoid receptor regulatory networkSMARCC2;SMARCA4;KRT17;POU2F1;EGR1;BGLAP;KRT14;NR1I3;CSN2

KRT17 has several biochemical functions, for example, MHC class II protein binding, MHC class II receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT17 itself. We selected most functions KRT17 had, and list some proteins which have the same functions with KRT17. You can find most of the proteins on our site.

Function Related Protein
MHC class II protein bindingCD74;CD4;MARCH8;LAG3;CD74A;KRT17;CD74B
MHC class II receptor activityHLA-DRA;HLA-DQA1;HLA-DRB1;HLA-DQB1;HLA-DRB4;HLA-DQB2;HLA-DRB3;HLA-DOB;HLA-DQA2
protein bindingHDDC3;ACTL7A;C6orf226;SNW1;ATF7;DYNC1LI1;PLP1;ACTR10;PRSS8
structural constituent of cytoskeletonACTB;SORBS2;KRT17;TUBB2B;F-KER;YEATS4;TUBA1L2;TUBA1L;ACTG1

KRT17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT17 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT17.

CCDC85B; USP1; UCHL1; KDM1A; SNAPIN; KRT6A; APC; ZDHHC17; midostaurin; EGFR; CFTR; GRB2; YWHAZ; NETO2; GABARAPL1

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can KRT17 protein be used as a prognostic indicator for cancer patients? 03/27/2021

Yes, elevated levels of KRT17 protein have been associated with poorer prognosis and higher risk of disease recurrence in cancer patients.

Can KRT17 protein levels be used to monitor treatment response in cancer patients? 01/12/2021

Yes, changes in KRT17 protein levels during treatment can serve as a potential biomarker for assessing treatment response and guiding personalized cancer therapy.

Are there any known associations between KRT17 protein and metastasis in cancer? 05/13/2018

Studies have suggested that higher KRT17 protein levels may be associated with increased metastatic potential in certain types of cancer.

How does KRT17 protein expression differ in normal tissue compared to cancerous tissue? 03/02/2017

KRT17 protein is typically expressed at low levels in normal tissue, but its expression is significantly upregulated in cancerous tissue.

Are there any specific diagnostic tests that measure KRT17 protein levels? 01/22/2016

Yes, immunohistochemistry and immunofluorescence assays are commonly used to measure KRT17 protein expression in cancer tissue samples.

Customer Reviews (3)

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Reviews
01/04/2021

    With its purity and reliability, this protein is poised to contribute significantly to the success of my research objectives by providing accurate and reproducible results.

    10/25/2019

      The KRT17 Protein demonstrates remarkable stability and functional efficiency, making it an indispensable tool for diverse scientific applications.

      10/26/2016

        Its versatility allows for exploration of its extensive involvement in various biochemical and biological processes, providing valuable insights into its role and implications.

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