CERS4

  • Official Full Name

    ceramide synthase 4

Recombinant Proteins

  • Human
  • Mouse
  • Bovine
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    CERS4 involved in several pathways and played different roles in them. We selected most pathways CERS4 participated on our site, such as Sphingolipid metabolism,Metabolic pathways,Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CERS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Sphingolipid metabolism UGCG,CERS1,SUMF2,SMPD5,SPTLC2A,SGPL1,PPAP2C,ARSH,ARSK,GALCA
    Sphingolipid signaling pathway TRADD,TP53,PLCB2,RAC3,FYN,PRKCB,SGPL1,PPP2R2A,HRAS,GNAQ
    Metabolic pathways ALDH9A1A.1,MGAT4A,GALNT3,SDHDB,NDUFB11,DAK,PKM,HSD3B6,GALM,NDUFA10

    Protein Function

    CERS4 has several biochemical functions, for example, DNA binding,sphingosine N-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CERS4 itself. We selected most functions CERS4 had, and list some proteins which have the same functions with CERS4. You can find most of the proteins on our site.

    Function Related Protein
    sphingosine N-acyltransferase activity CERS3B,CERS5,LASS2,CERS2,CERS2A,LASS5,LASS4,FAM57B,LASS1,CERS4A
    DNA binding ACD,DLX5A,SCRT2,SP110,ZNF576.2,POU5F2,PAX6A,KAT6B,SP6,SIX9

    Interacting Protein

    CERS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CERS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CERS4.

    ltp_ebvg

    Resources

    References

    • Ebel, P; Imgrund, S; et al. Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia. BIOCHEMICAL JOURNAL 461:147-158(2014).

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