MRPL51

  • Official Full Name

    mitochondrial ribosomal protein L51

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q.
  • Synonyms

    MRPL51; mitochondrial ribosomal protein L51; mitochondrial ribosomal protein 64 , MRP64; 39S ribosomal protein L51, mitochondrial; bMRP64; CDA09; HSPC241; L51mt; MRP-L51; bMRP-64; mitochondrial ribosomal protein 64; mitochondrial ribosomal protein bMRP64;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL51-4158HCL Recombinant Human MRPL51 293 Cell Lysate HEK293 N/A
Human MRPL51-5595H Recombinant Human MRPL51 Protein, GST-tagged Wheat Germ GST
Human MRPL51-6442HF Recombinant Full Length Human MRPL51 Protein, GST-tagged In Vitro Cell Free System GST 128 amino acids
Mouse MRPL51-10078M Recombinant Mouse MRPL51 Protein Mammalian Cell His
Mouse MRPL51-5708M Recombinant Mouse MRPL51 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MRPL51-5708M-B Recombinant Mouse MRPL51 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MRPL51-2850R Recombinant Rhesus monkey MRPL51 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MRPL51-2670R Recombinant Rhesus Macaque MRPL51 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MRPL51-2670R-B Recombinant Rhesus Macaque MRPL51 Protein Pre-coupled Magnetic Beads HEK293
Chicken MRPL51-1860C Recombinant Chicken MRPL51 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MRPL51 involved in several pathways and played different roles in them. We selected most pathways MRPL51 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL51 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mitochondrial translationDAP3;MRPL49;MRPL54;CHCHD1;MRPL47;MRPL40;MRPL48;MRPS25;TUFM
Mitochondrial translation elongationMRPL55;MRPL44;MRPS35;MRPS30;TUFM;MRPL38;MRPL49;AURKAIP1;MRPL45
Mitochondrial translation initiationMRPL45;MTFMT;MRPL44;MRPL46;MRPS36;MRPL47;GADD45GIP1;CHCHD1;MRPS31
Mitochondrial translation terminationDAP3;GADD45GIP1;MRPL49;MRPL38;MRPL46;MRPS22;MRPS23;MRPS33;MRPL47
Organelle biogenesis and maintenanceCEP89;CHCHD1;MRPL47;MRPL49;NPHP4;TCTN3;TCTEX1D1;TUFM;WDR35

MRPL51 has several biochemical functions, for example, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL51 itself. We selected most functions MRPL51 had, and list some proteins which have the same functions with MRPL51. You can find most of the proteins on our site.

Function Related Protein
protein bindingDNAJB9;CNIH4;POMP;UCHL1;C10orf33;NCOA5;NR1I2;FBXL3;PFKM
structural constituent of ribosomeRPL35A;RPS17;RPS8B;MRPS25;MRPS5;RPS26L;MRPL10;RPL36AL;SLC25A47A

MRPL51 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL51 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL51.

ICT1; MRPL50; MRPL9

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