• Official Full Name
  • plakophilin 2
  • Background
  • This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008]
  • Synonyms
  • PKP2; plakophilin 2; ARVD9; plakophilin-2;
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PKP2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PKP2
Source (Host):Species:Human
Product nameRecombinant Human PKP2 293 Cell Lysate

PKP2 Related Articles

Rickelt, S; et al. Plakophilin-2: a cell-cell adhesion plaque molecule of selective and fundamental importance in cardiac functions and tumor cell growth. CELL AND TISSUE RESEARCH 348:281-294(2012).
Rickelt, S; Rizzo, S; et al. A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata. MODERN PATHOLOGY 23:1429-1437(2010).