SLC26A1
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Official Full Name
solute carrier family 26 (sulfate transporter), member 1 -
Overview
This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. -
Synonyms
SLC26A1;solute carrier family 26 (sulfate transporter), member 1;sulfate anion transporter 1;EDM4;SAT 1;sulfate transporter;sulfate anion tranporter AT1;solute carrier family 26 member 1;sulfate/anion transporter SAT-1 protein;SAT1;SAT-1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC26A1-15337M | Recombinant Mouse SLC26A1 Protein | Mammalian Cells | Mouse | His |
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| SLC26A1-5145Z | Recombinant Zebrafish SLC26A1 | Mammalian Cells | Zebrafish | His |
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| SLC26A1-8298M | Recombinant Mouse SLC26A1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SLC26A1-8298M-B | Recombinant Mouse SLC26A1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC26A1 involved in several pathways and played different roles in them. We selected most pathways SLC26A1 participated on our site, such as Biological oxidations,Cytosolic sulfonation of small molecules,Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC26A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of carbohydrates | SLC25A11,B3GNT2A,PYGMB,DSEL,B3GNT1,EPM2A,SLC35D2,B3GNT2,MAPK1IP1L,SLC25A1 |
| Multifunctional anion exchangers | SLC26A3.2,SLC26A6L,SLC26A2,SLC26A7,SLC26A3,SLC26A3.1 |
| Metabolism | COX16,SLC35B3,FAM36A,CKMT2,ARV1,FIG4,SULT1B1,PCBD1,NUDT3,HAS1 |
| Biological oxidations | GGT6,CYP11A1,CYP4A11,CYP26A1,ADH6,GSTO2,ADH1C,CYP2R1,CYP2C19,ABHD10 |
| Glycosaminoglycan metabolism | UST,HS3ST6,PRELP,HS3ST4,HAS3,HAS1,CHST14,KIAA1199,B3GNT2A,CHP |
| SLC-mediated transmembrane transport | SLC27A4,SLC26A3,SLCO2A1,SLC4A2B,SLC10A6,CP,SLC43A1B,SLC12A1,SLC31A1,SLC35A3B |
| Cytosolic sulfonation of small molecules | SULT2ST2,SLC35B3,SULT1ST6,SLC35B2,SLC26A2,BPNT1,SULT1B1,SULT1C4,Sult2a6,SULT1ST5 |
| Phase II conjugation | GLYATL1,SULT1C4,UGT1B7,SLC26A2,AS3MT,Sult2a6,SULT1B1,SLC35B2,Sult2a2,ABHD14B |
Protein Function
SLC26A1 has several biochemical functions, for example, anion:anion antiporter activity,antiporter activity,bicarbonate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC26A1 itself. We selected most functions SLC26A1 had, and list some proteins which have the same functions with SLC26A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel activity | CLCA5,CLIC4,CLIC6,APOL1,GABRA6,CLCC1,SLC26A7,TTYH3,CLCA1,GABRR3 |
| sulfate transmembrane transporter activity | SLC26A2,SLC26A3.1,SLC26A6,SLC26A9,SLC26A3.2,SLC26A6L,SLC26A7,SLC26A3,SLC26A11,SLC26A5 |
| bicarbonate transmembrane transporter activity | CFTR,SLC26A9,SLC26A3.2,SLC26A6,SLC4A1,SLC26A3,SLC26A11,SLC26A7,SLC4A1B,SLC26A2 |
| anion:anion antiporter activity | SLC4A11,SLC26A11,SLC4A1B,SLC4A1,SLC26A3.2,SLC26A3.1,SLC26A9,SLC4A2A,SLC26A6,SLC26A6L |
| antiporter activity | TMEM241,SLC9A6B,SLC7A13,SLC9A3.1,CLCN4,SLC7A4,SLC9A3.2,SLC35E3,SLC35C2,SLC7A10 |
| chloride transmembrane transporter activity | SLC26A3,SLC4A1,CFTR,Slc4a2,SLC26A4,SLC26A6 |
| secondary active sulfate transmembrane transporter activity | SLC26A6L,SLC26A3.2,SLC26A9,SLC26A3,SLC26A7,SLC26A2,SLC26A4,SLC26A5,SLC26A11,SLC26A6 |
| oxalate transmembrane transporter activity | SLC26A3.1,SLC26A5,SLC26A2,SLC26A3,SLC26A6L,SLC26A7,SLC26A3.2,SLC26A4,SLC26A6,SLC26A11 |
Interacting Protein
SLC26A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC26A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC26A1.
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References
- Brzica, H; Breljak, D; et al. OXALATE: FROM THE ENVIRONMENT TO KIDNEY STONES. ARHIV ZA HIGIJENU RADA I TOKSIKOLOGIJU-ARCHIVES OF INDUSTRIAL HYGIENE AND TOXICOLOGY 64:609-630(2013).
- Pitule, P; Vycital, O; et al. Differential Expression and Prognostic Role of Selected Genes in Colorectal Cancer Patients. ANTICANCER RESEARCH 33:4855-4865(2013).
