SLC26A1

  • Official Full Name

    solute carrier family 26 (sulfate transporter), member 1
  • Overview

    This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified.
  • Synonyms

    SLC26A1;solute carrier family 26 (sulfate transporter), member 1;sulfate anion transporter 1;EDM4;SAT 1;sulfate transporter;sulfate anion tranporter AT1;solute carrier family 26 member 1;sulfate/anion transporter SAT-1 protein;SAT1;SAT-1
Cat.# Product name Source (Host) Species Tag Protein Length Price
SLC26A1-15337M Recombinant Mouse SLC26A1 Protein Mammalian Cells Mouse His
SLC26A1-5145Z Recombinant Zebrafish SLC26A1 Mammalian Cells Zebrafish His
SLC26A1-8298M Recombinant Mouse SLC26A1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
SLC26A1-8298M-B Recombinant Mouse SLC26A1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SLC26A1 involved in several pathways and played different roles in them. We selected most pathways SLC26A1 participated on our site, such as Biological oxidations,Cytosolic sulfonation of small molecules,Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC26A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of carbohydrates SLC5A2,SLC25A1A,SLC5A4,CHST14,LYVE1,TREH,SLC25A11,SLC5A9,HAS3,UST
    Metabolism COX14,PROZA,CTRC,NAGS,C20orf7,MED15,COX18,CKMT2A,TMEM195,NUDT4B
    Biological oxidations UGT1B7,CYP2K8,CYP2D6,ABHD14B,CYP1A1,CYP2C18,SULT1B1,SULT4A1,CYP2V1,CYP27A1
    Glycosaminoglycan metabolism B3GNT2A,KIAA1199,BGNA,SLC35B2,FMODA,HAS1,B4GALT7,HS3ST6,CSPG5B,B3GNT1
    Cytosolic sulfonation of small molecules SULT1C4,SLC35B3,SULT1B1,ABHD14B,SULT1ST6,SULT2ST1,SULT4A1,Sult2a6,Sult2a2,SULT1ST5
    SLC-mediated transmembrane transport SLC29A1A,SLC8A2A,SLCO2B1,RHCG2A,SLC29A3,SLC20A1B,SLC27A4,SLC35A3A,SLC6A7,SLC1A3A
    Phase II conjugation SULT1ST6,GGTLC1,UGT1B7,UGT1B1,SULT2ST2,SULT1C2,SULT1ST5,SULT1C4,SLC35B3,AS3MT
    Multifunctional anion exchangers SLC26A2,SLC26A6L,SLC26A3.2,SLC26A3.1,SLC26A3,SLC26A7

    Protein Function

    SLC26A1 has several biochemical functions, for example, anion:anion antiporter activity,antiporter activity,bicarbonate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC26A1 itself. We selected most functions SLC26A1 had, and list some proteins which have the same functions with SLC26A1. You can find most of the proteins on our site.

    Function Related Protein
    chloride channel activity FXYD1,TTYH3,GABRG2,GABRA2,FXYD3,TTYH2,SLC26A4,CLIC5A,GABRD,SLC26A3.2
    antiporter activity SLC38A3,SLC7A6,CLCN4,SLC35E3,SLC35E1,SLC7A14,SLC35C2,SLC26A3.1,SLC25A16,CLCN3
    bicarbonate transmembrane transporter activity CFTR,SLC26A3,SLC4A1B,SLC26A11,SLC26A2,SLC26A4,SLC26A7,SLC26A6,SLC4A11,SLC26A3.2
    anion:anion antiporter activity SLC26A5,SLC4A2B,SLC26A3,SLC26A3.2,SLC26A6,SLC26A2,SLC4A1,SLC4A1B,SLC4A2A,Slc4a2
    chloride transmembrane transporter activity SLC26A6,Slc4a2,SLC4A1,SLC26A3,CFTR,SLC26A4
    secondary active sulfate transmembrane transporter activity SLC13A1,SLC26A7,SLC26A3.1,SLC26A5,SLC26A6L,SLC26A2,SLC26A6,SLC26A9,SLC26A11,SLC26A4
    oxalate transmembrane transporter activity SLC26A4,SLC26A3,SLC26A6,SLC26A6L,SLC26A5,SLC26A3.1,SLC26A2,SLC26A7,SLC26A3.2,SLC26A9
    sulfate transmembrane transporter activity SLC26A6,SLC26A7,SLC26A9,SLC26A6L,SLC26A4,SLC26A3,SLC26A11,SLC26A2,SLC26A3.1,SLC26A5

    Interacting Protein

    SLC26A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC26A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC26A1.

    Resources

    References

    • Brzica, H; Breljak, D; et al. OXALATE: FROM THE ENVIRONMENT TO KIDNEY STONES. ARHIV ZA HIGIJENU RADA I TOKSIKOLOGIJU-ARCHIVES OF INDUSTRIAL HYGIENE AND TOXICOLOGY 64:609-630(2013).
    • Pitule, P; Vycital, O; et al. Differential Expression and Prognostic Role of Selected Genes in Colorectal Cancer Patients. ANTICANCER RESEARCH 33:4855-4865(2013).

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