vps45

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vps45

Official Full Name vacuolar protein sorting 45 homolog (S. cerevisiae)
Background Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
Synonyms VPS45; vacuolar protein sorting 45 homolog (S. cerevisiae); vacuolar protein sorting 45A (yeast homolog) , vacuolar protein sorting 45A (yeast) , VPS45A, VPS45B; vacuolar protein sorting-associated protein 45; h vps45; H1; h-VPS45; H1VPS45; HGNC:14579; hlVps45; Leucocyte vacuolar protein sorting 45; OTTHUMP00000014482; Vacuolar protein sorting 45A (yeast homolog); Vacuolar protein sorting 45A; Vacuolar protein sorting 45B (yeast); VPS45_HUMAN; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Vps45-6943M Recombinant Mouse Vps45 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human VPS45-384HCL Recombinant Human VPS45 293 Cell Lysate HEK293 N/A
    Mouse VPS45-18379M Recombinant Mouse VPS45 Protein Mammalian Cell His
    Rat VPS45-6544R Recombinant Rat VPS45 Protein Mammalian Cell His
    Chicken VPS45-3233C Recombinant Chicken VPS45 Mammalian Cell His
    Zebrafish VPS45-8184Z Recombinant Zebrafish VPS45 Mammalian Cell His

    vps45 involved in several pathways and played different roles in them. We selected most pathways vps45 participated on our site, such as Endocytosis, Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with vps45 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis SNX32; TGFB1A; PIP5K1AB; EHD4; FGFR4; MHC1UXA2; SH3GL3; RAB10; IGF2R; GIT2B
    Factors involved in megakaryocyte development and platelet production CENPE; BA2; DOCK8; EHD1; HBG1; KIF4; OSTN; HMG20B; KIF18A; H3F3B.1
    Hemostasis IRF2; SLC8A2A; SERPINA1L; SERPINE2; KIFAP3; DGKQ; ANXA2A; HBD; APOER2; SRGN

    vps45 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by vps45 itself. We selected most functions vps45 had, and list some proteins which have the same functions with vps45. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function OTULINA; SLC35A5; TMEM120B; ATXN7L2A; TAS2R125; FBXO24; Sez6l; PDK3B; ARL14EPL; MCART1
    protein binding CCP110; TUFT1; PGAP2; PPP1R37; NOMO2; FKBP5; SORBS3; HSPB11; SLC35A2; PRKCQ

    vps45 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with vps45 here. Most of them are supplied by our site. Hope this information will be useful for your research of vps45.

    RBSN; BCAR3; IGF1R; PTPN1; PAX2; CASP8; RB1CC1; gtp; pi3p; ere_dna

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