VPS45

  • Official Full Name

    vacuolar protein sorting 45 homolog (S. cerevisiae)

  • Overview

    Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
  • Synonyms

    VPS45; vacuolar protein sorting 45 homolog (S. cerevisiae); vacuolar protein sorting 45A (yeast homolog) , vacuolar protein sorting 45A (yeast) , VPS45A, VPS45B; vacuolar protein sorting-associated protein 45; h vps45; H1; h-VPS45; H1VPS45; HGNC:14579; hlVps45; Leucocyte vacuolar protein sorting 45; OTTHUMP00000014482; Vacuolar protein sorting 45A (yeast homolog); Vacuolar protein sorting 45A; Vacuolar protein sorting 45B (yeast); VPS45_HUMAN; VPS45A; VPS45B; VPS54A; VSP45; VSP45A;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VPS45-384HCL Recombinant Human VPS45 293 Cell Lysate HEK293 N/A
Mouse VPS45-18379M Recombinant Mouse VPS45 Protein Mammalian Cell His
Mouse Vps45-6943M Recombinant Mouse Vps45 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse VPS45-10071M-B Recombinant Mouse VPS45 Protein Pre-coupled Magnetic Beads HEK293
Mouse VPS45-10071M Recombinant Mouse VPS45 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat VPS45-6544R Recombinant Rat VPS45 Protein Mammalian Cell His
Rat VPS45-6200R Recombinant Rat VPS45 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat VPS45-6200R-B Recombinant Rat VPS45 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish VPS45-8184Z Recombinant Zebrafish VPS45 Mammalian Cell His
Chicken VPS45-3233C Recombinant Chicken VPS45 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

VPS45 involved in several pathways and played different roles in them. We selected most pathways VPS45 participated on our site, such as Endocytosis, Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS45 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisCLTCB;ARPC4L;VPS4A;ASAP2;WIPF1;HSPA1B;CDC42L2;ARF6A;CAPZA2
Factors involved in megakaryocyte development and platelet productionMAFGB;DOCK1;HBBE3;KDM1A;KIF15;KIF22;GATA6;DOCK10;MYB
HemostasisSERPINB8;CBX5;SRGN;ITGB3A;CFD;KCNMB1;KIF22;ANXA2;HRG

VPS45 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS45 itself. We selected most functions VPS45 had, and list some proteins which have the same functions with VPS45. You can find most of the proteins on our site.

Function Related Protein
molecular_functionVSTM4A;TMEM57;LY9;EMILIN3;TSPAN3;TMEM222A;COMMD4;Armc3;NANOS1
protein bindingNAA30;GKAP1;FAM119A;POU2AF1;NOL4;KLHL35;NEFM;PAK2;HIST1H2AL

VPS45 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS45 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS45.

RBSN; BCAR3; IGF1R; PTPN1; PAX2; CASP8; RB1CC1; gtp; pi3p; ere_dna

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