b3galtl
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  • Official Full Name
  • beta 1,3-galactosyltransferase-like
  • Background
  • The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).
  • Synonyms
  • B3GALTL; beta 1,3-galactosyltransferase-like; beta-1,3-glucosyltransferase; B3Glc T; B3GTL; B3GlcT; Beta 1,3 galactosyltransferase like; Beta 3 galactosyltransferase like; Beta3GlcT; Galactosyltransferase; GalT; beta 3-glycosyltransferase-like; beta-3-glycosyltransferase-like; UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like; Gal-T; B3Glc-T; beta3Glc-T
Cat.#:B3GALTL-013HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human B3GALTL protein, GST-tagged
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Cat.#:B3GALTL-10098HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human B3GALTL, GST-tagged
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Cat.#:B3GALTL-459HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human B3GALTL, His tagged
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Cat.#:B3GALTL-2235MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse B3GALTL Protein
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Cat.#:B3GALTL-1103HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human B3GALTL cell lysate
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Involved Pathway

B3GALTL involved in several pathways and played different roles in them. We selected most pathways B3GALTL participated on our site, such as Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GALTL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism of proteins
FURINA; SUMF2; SFTPB; DAD1; CALCA; ST6GAL2B; NAPAB; EIF5; KIFC3; NSFB
O-glycosylation of TSR domain-containing proteins
SSPO; SPON2; ADAMTSL3; C8orf84; ADAMTS20; ADAMTS8; ADAMTSL4; B3GALTL; ADAMTS5; ADAMTSL1
O-linked glycosylation
ADAMTSL1; ADAMTS13; ADAMTS1; SPON2; ADAMTSL4; MUC20; ADAMTSL5; ADAMTS10; B3GNT8; MUCL1
Other types of O-glycan biosynthesis
FUT4; OGT.1; GLT25D1; POGLUT1; FUT9A; ST3GAL3B; B3GALTLA; PLOD3; MGAT5B; POMT2
Post-translational protein modification
TRAPPC6BL; ADAMTS13; ARSD; MCFD2; PIGK; ST6GAL2B; NANP; MUC15; ADAMTS5; ATPBD4

Protein Function

B3GALTL has several biochemical functions, for example, transferase activity, transferring glycosyl groups. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GALTL itself. We selected most functions B3GALTL had, and list some proteins which have the same functions with B3GALTL. You can find most of the proteins on our site.
Function
Related Protein
Function transferase activity, transferring glycosyl groups
Related Protein PNP6; UGT2B3; EXT1A; PYGMB; PYGMA; POMGNT2; UGT5C3; B3GAT1A; B3GNT5A; UGT1A5

Interacting Protein

B3GALTL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GALTL here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GALTL.
FGFR1OP; AK1; EMC2; SMC6

B3GALTL Related Articles

Reis, LM; Semina, EV; et al. Genetics of anterior segment dysgenesis disorders. CURRENT OPINION IN OPHTHALMOLOGY 22:314-324(2011).
Aliferis, K; Marsal, C; et al. A novel nonsense B3GALTL mutation confirms Peters plus syndrome in a patient with multiple malformations and Peters anomaly. OPHTHALMIC GENETICS 31:205-208(2010).