capn9
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  • Official Full Name
  • calpain 9
  • Background
  • Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms
  • CAPN9; calpain 9; GC36; nCL-4; calpain-9; new calpain 4; novel calpain large subunit-4; digestive tract-specific calpain;
Cat.#:CAPN9-0371HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CAPN9 Protein, GST-Tagged
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Cat.#:CAPN9-10707HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CAPN9, His-tagged
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Cat.#:CAPN9-2700MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CAPN9 Protein
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Cat.#:CAPN9-942ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CAPN9
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Cat.#:CAPN9-7859HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CAPN9 293 Cell Lysate
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Involved Pathway

CAPN9 involved in several pathways and played different roles in them. We selected most pathways CAPN9 participated on our site, such as Integrin-mediated cell adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPN9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Integrin-mediated cell adhesion
MAPK4; CAPN10; MYLK2; CAPN3; CAPNS1; CAPN3A; CAPN11; CAPN5; TNS1; SEPP1

Protein Function

CAPN9 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPN9 itself. We selected most functions CAPN9 had, and list some proteins which have the same functions with CAPN9. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PROCA; EPDL1; NID1; RAB11FIP3; EFCAB10; SCUBE3; CRB1; S100S; PCDH11Y; MASP2
Function calcium-dependent cysteine-type endopeptidase activity
Related Protein PEF1; CAPN12; CAPN2A; CAPN1; CAPN5A; CAPNS1; CAPN3; CAPNS1A; CAPN2; CAPN2B

CAPN9 Related Articles

Soslau, G; Mason, C; et al. Intracellular matrix metalloproteinase-2 (MMP-2) regulates human platelet activation via hydrolysis of talin. THROMBOSIS AND HAEMOSTASIS 111:140-153(2014).
Samanta, S; Ghoshal, A; et al. Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis. PLOS ONE 7:-(2012).