• Official Full Name
  • Chordin-Like 2
  • Background
  • CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. A member of the chordin family of proteins, it contains a signal peptide and three CR (cysteine-rich repeat) domains. When expressed as a recombinant protein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
  • Synonyms
  • CHRDL2; chordin-like 2; BNF1; CHL2; FKSG37; DKFZp586N2124; chordin-like protein 2; BNF-1; chordin-related protein 2; breast tumor novel factor 1; OTTHUMP00000230490; OTTHUMP00000230491; OTTHUMP00000230494
Source (Host):HEK293Species:Human
Product nameRecombinant Human CHRDL2 Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chrdl2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CHRDL2 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CHRDL2

Protein Function

CHRDL2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRDL2 itself. We selected most functions CHRDL2 had, and list some proteins which have the same functions with CHRDL2. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein GTF2I; FGA; NGDN; KHDC3; MAPK8IP3; IL7; SIRPB1; GRM2; NEK8; ZDHHC13