DDX17 Protein, DEAD (Asp-Glu-Ala-Asp) box polypeptide 17


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Official Full Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.
Synonyms DDX17; DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17 (72kD); probable ATP-dependent RNA helicase DDX17; P72; RH70; DDX17_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 17; DEAD box protein 17; DEAD box protein p72; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17; RNA dependent helicase p72; RNA-dependent helicase p72; OTTHUMP00000199223; OTTHUMP00000199224; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DDX17-207H Recombinant Human DDX17 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DDX17-28323TH Recombinant Human DDX17 Wheat Germ N/A
    Human DDX17-7020HCL Recombinant Human DDX17 293 Cell Lysate HEK293 N/A
    Human DDX17-85H Recombinant Human DDX17, GST-tagged Wheat Germ GST
    Mouse DDX17-4400M Recombinant Mouse DDX17 Protein Mammalian Cell His

    DDX17 involved in several pathways and played different roles in them. We selected most pathways DDX17 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    DDX17 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX17 itself. We selected most functions DDX17 had, and list some proteins which have the same functions with DDX17. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding JAK3; DGKD; PAK1; RRM1; Acsm2a; PRKAG3; ACACA; SRC; ACTB2; ABCE1
    ATP-dependent RNA helicase activity DHX35; DDX19A; ACTG2; DDX28; SUPV3L1; DDX42; DDX47; TMEM38A; DDX50; TDRD12
    RNA helicase activity DDX6; CTU1; CHST13; DDX10; DDX5; CCDC111; SKIV2L2; DDX24; UAP1L1; DHX15
    RNA-dependent ATPase activity YTHDC2; IGHMBP2; DDX17; DDX39B
    estrogen receptor binding PHB2; HSD17B10; LEF1; NSD1; NKX3; NKX3-1; PPID; ARRB1; MMS19; DDX17
    poly(A) RNA binding HIST1H47; MRPL37; MRPS5; TRMT1L; SNRPN; PRPF3; ZFP346; HTATSF1; CPSF7; RSRC2
    protein binding FAF1; SCARA5; NFS1; CCDC53; ORC4L; RRAGC; AIG1; RBBP6; CSTF2T; VPS35
    transcription coactivator activity SMARCE1; MAML1; KAT6A; HAND1; HTATIP2; ZEB1; USP22; PDLIM1; ESRRB; GTF2F1

    DDX17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX17 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX17.


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