|Official Full Name||DEAD (Asp-Glu-Ala-Asp) box polypeptide 17|
|Background||DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.|
|Synonyms||DDX17; DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17 (72kD); probable ATP-dependent RNA helicase DDX17; P72; RH70; DDX17_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 17; DEAD box protein 17; DEAD box protein p72; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17; RNA dependent helicase p72; RNA-dependent helicase p72; OTTHUMP00000199223; OTTHUMP00000199224; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
DDX17 involved in several pathways and played different roles in them. We selected most pathways DDX17 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
DDX17 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX17 itself. We selected most functions DDX17 had, and list some proteins which have the same functions with DDX17. You can find most of the proteins on our site.
|ATP binding||JAK3; DGKD; PAK1; RRM1; Acsm2a; PRKAG3; ACACA; SRC; ACTB2; ABCE1|
|ATP-dependent RNA helicase activity||DHX35; DDX19A; ACTG2; DDX28; SUPV3L1; DDX42; DDX47; TMEM38A; DDX50; TDRD12|
|RNA binding||KHSRP; CNOT7; EXOSC5; D19BWG1357E; RDM1; BICC1; CELF1; QKI2; RPUSD1; PTBP1A|
|RNA helicase activity||DDX6; CTU1; CHST13; DDX10; DDX5; CCDC111; SKIV2L2; DDX24; UAP1L1; DHX15|
|RNA-dependent ATPase activity||YTHDC2; IGHMBP2; DDX17; DDX39B|
|estrogen receptor binding||PHB2; HSD17B10; LEF1; NSD1; NKX3; NKX3-1; PPID; ARRB1; MMS19; DDX17|
|poly(A) RNA binding||HIST1H47; MRPL37; MRPS5; TRMT1L; SNRPN; PRPF3; ZFP346; HTATSF1; CPSF7; RSRC2|
|protein binding||FAF1; SCARA5; NFS1; CCDC53; ORC4L; RRAGC; AIG1; RBBP6; CSTF2T; VPS35|
|transcription coactivator activity||SMARCE1; MAML1; KAT6A; HAND1; HTATIP2; ZEB1; USP22; PDLIM1; ESRRB; GTF2F1|
DDX17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX17 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX17.
ESR1; SF1; DROSHA; YAP1