• Official Full Name
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
  • Background
  • DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.
  • Synonyms
  • DDX17; DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17 (72kD); probable ATP-dependent RNA helicase DDX17; P72; RH70; DDX17_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 17; DEAD box protein 17; DEAD box protein p72; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17; RNA dependent helicase p72; RNA-dependent helicase p72; OTTHUMP00000199223; OTTHUMP00000199224; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)
Source (Host):HEK293Species:Human
Product nameRecombinant Human DDX17 Protein, MYC/DDK-tagged
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human DDX17
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human DDX17, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DDX17 Protein
Source (Host):Species:Human
Product nameRecombinant Human DDX17 293 Cell Lysate

Protein Function

DDX17 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX17 itself. We selected most functions DDX17 had, and list some proteins which have the same functions with DDX17. You can find most of the proteins on our site.
Related Protein
Function ATP binding
Related Protein TSSK4; ERBB3A; VARS2; SMYHC1; ABCB4; AK3; NUAK2; AARS2; INO80; THG1L
Function ATP-dependent RNA helicase activity
Related Protein G3BP1; DHX32; TDRD9; DDX17; DDX5; DDX24; DDX54; EIF4A3; DDX50; DDX28
Function RNA binding
Related Protein EIF2S1B; RBM4B; RPL18A; PRAC; RTCD1; RPS7; ILF3A; DDX19A; SURF6; RDM1
Function RNA helicase activity
Related Protein PRIM2; UAP1L1; DHX15; DDX10; SKIV2L2; CHST13; CCDC111; DDX24; DDX5; CTU1
Function RNA-dependent ATPase activity
Related Protein YTHDC2; IGHMBP2; DDX17; DDX39B
Function estrogen receptor binding
Related Protein PADI2; MED1; DDX54; DDX5; TMEM38A; XBP1; NKX3-1; PPARG; NKX3; CNOT1
Function poly(A) RNA binding
Function protein binding
Related Protein DARS2; ABHD14B; CLINT1; C1R; ASB13; KRIT1; FLNA; TIMP3; LAPTM4B; RAMP2
Function transcription coactivator activity
Related Protein NACA; VGLL1; USP22; GATA4; ABRA; RFXAP; MED16; NFE2; POU2AF1; UBE2L3

Interacting Protein

DDX17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX17 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX17.