• Official Full Name
  • DEAD (Asp-Glu-Ala-Asp) box helicase 56
  • Background
  • Nucleolar Helicase is an enzyme that in humans is encoded by the DDX56 gene. This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit.
  • Synonyms
  • DDX56; DEAD (Asp-Glu-Ala-Asp) box helicase 56; DEAD (Asp Glu Ala Asp) box polypeptide 56; probable ATP-dependent RNA helicase DDX56; NOH61; nucleolar helicase of 61 kDa; DEAD box protein 21; DEAD box protein 56; DEAD-box RNA helicase; 61-kd nucleolar heli
Source (Host):HEK293Species:Human
Product nameRecombinant Human DDX56 Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DEAD (Asp-Glu-Ala-Asp) box helicase 56, His-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DDX56 protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DDX56
Source (Host):Species:Human
Product nameRecombinant Human DDX56 293 Cell Lysate

Protein Function

DDX56 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX56 itself. We selected most functions DDX56 had, and list some proteins which have the same functions with DDX56. You can find most of the proteins on our site.
Related Protein
Function ATP binding
Related Protein MAP4K6; NEK5; CSNK1A1L; STK19; ABCG3; KIF2B; BMPR1AA; STK35; MYO3A; MAP2K5
Function ATP-dependent RNA helicase activity
Related Protein DDX19B; SKIV2L; DHX35; DHX15; DHX33; BAT1; DDX3; DDX18; DHX29; EIF4A1B
Function poly(A) RNA binding
Related Protein HIST4H4; TCERG1; CFAP20; SPATS2; RPS6; FAM133B; SNIP1; RPS23; AKAP1; CPEB2

Interacting Protein

DDX56 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX56 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX56.
q96sz0_human; TBC1D4; MRPS14; FURIN; FBL; SRP14; RPS9; RPL29; RPL34; RPS3A; RPL26; RPL37; RPS16; RPS29; RPS11