| Description : |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to beinvolved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-strandedRNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
113.7 kDa |
| AA Sequence : |
MPGKLRSDAGLESDTAMKKGETLRK QTEEKEKKEKPKSDKTEEIAEEEET VFPKAKQVKKKAEPSEVDMNSPKSK KAKKKEEPSQNDISPKTKSLRKKKE PIEKKVVSSKTKKVTKNEEPSEEEI DAPKPKKMKKEKEMNGETREKSPKL KNGFPHPEPDCNPSEAASEESNSEI EQEIPVEQKEGAFSNFPISEETIKL LKGRGVTFLFPIQAKTFHHVYSGKD LIAQARTGTGKTFSFAIPLIEKLHG ELQDRKRGRAPQVLVLAPTRELANQ VSKDFSDITKKLSVACFYGGTPYGG QFERMRNGIDILVGTPGRIKDHIQN GKLDLTKLKHVVLDEVDQMLDMGFA DQVEEILSVAYKKDSEDNPQTLLFS ATCPHWVFNVAKKYMKSTYEQVDLI GKKTQKTAITVEHLAIKCHWTQRAA VIGDVIRVYSGHQGRTIIFCETKKE AQELSQNSAIKQDAQSLHGDIPQKQ REITLKGFRNGSFGVLVATNVAARG LDIPEVDLVIQSSPPKDVESYIHRS GRTGRAGRTGVCICFYQHKEEYQLV QVEQKAGIKFKRIGVPSATEIIKAS SKDAIRLLDSVPPTAISHFKQSAEK LIEEKGAVEALAAALAHISGATSVD QRSLINSNVGFVTMILQCSIEMPNI SYAWKELKEQLGEEIDSKVKGMVFL KGKLGVCFDVPTASVTEIQEKWHDS RRWQLSVATEQPELEGPREGYGGFR GQREGSRGFRGQRDGNRRFRGQREG SRGPRGQRSGGGNKSNRSQNKGQKR SFSKAFGQ |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
