defb105a
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  • Official Full Name
  • defensin, beta 105A
  • Background
  • Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy.
  • Synonyms
  • DEFB105A; defensin, beta 105A; DEFB105, defensin, beta 105; beta-defensin 105; DEFB 5; BD5; Beta defensin 105 precursor; DEFB105; DEFB5; Defensin beta 105; beta defensin 5; beta-defensin 5; defensin, beta 5; BD-5; DEFB-5; DEFB105B