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Recombinant Human DEFB105A protein

Cat.No. : DEFB105A-7377H
Product Overview : Recombinant Human DEFB105A protein was expressed in E.coli.
  • Specification
  • Gene Information
  • Related Products
Description : Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy.
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.
Molecular Mass : Approximately 5.8 kDa, a single non-glycosylated polypeptide chain containing 51 amino acids.
Protein length : 51
AA Sequence : GLDFSQPFPSGEFAVCESCKLGRGK CRKECLENEKPDGNCRLNFLCCRQR I
Endotoxin : Less than 1.0 EU/µg of rHuBD-5 as determined by LAL method.
Purity : >95% by SDS-PAGE and HPLC analyses.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : DEFB105A
Official Symbol : DEFB105A
Synonyms : BD-5; DEFB-5; DEFB105
Gene ID : 245908
mRNA Refseq : NM_152250.2
Protein Refseq : NP_689463.1
UniProt ID : Q8NG35

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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