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DLG5

Official Full Name

discs, large homolog 5 (Drosophila)
Overview

This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined.
Synonyms

DLG5; discs, large homolog 5 (Drosophila); discs, large (Drosophila) homolog 5; disks large homolog 5; KIAA0583; P dlg; Discs large homolog 5 (Drosophila); Discs large homolog 5; Discs large protein LP DLG; Discs large protein P dlg; Discs large protein P-dlg; DLG 5; DLG5_HUMAN; Large type of P DLG; LP DLG; P DLG5; PDLG; Placenta and prostate DLG; OTTHUMP00000019917; OTTHUMP00000019918; large type of P-DLG; discs large protein LP-DLG; LP-DLG; P-DLG5;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	DLG5-7832H	Recombinant Human DLG5 protein, His & T7-tagged	E.coli	His/T7	Asp1722~Asn1905 (Accession # Q8TDM6)	Inquiry
Human	DLG5-2679H	Recombinant Human DLG5 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	DLG5-2267H	Recombinant Human DLG5 Protein (Asp1722-Asn1905), N-His tagged	E.coli	N-His	Asp1722-Asn1905	Inquiry
Mouse	Dlg5-7833M	Recombinant Mouse Dlg5 protein, His & T7-tagged	E.coli	His/T7	Asp1724~Ser1917 (Accession # E9Q9R9)	Inquiry

DLG5 involved in several pathways and played different roles in them. We selected most pathways DLG5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DLG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

DLG5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DLG5 itself. We selected most functions DLG5 had, and list some proteins which have the same functions with DLG5. You can find most of the proteins on our site.

Function	Related Protein

DLG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLG5.