• Official Full Name
  • dipeptidyl-peptidase 8
  • Background
  • This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Synonyms
  • DPP8; dipeptidyl-peptidase 8; DP8; DPRP1; MSTP141; dipeptidyl peptidase 8; DPRP-1; DPP VIII; dipeptidylpeptidase 8; prolyl dipeptidase DPP8; dipeptidyl peptidase VIII; dipeptidyl peptidase IV-related protein 1; dipeptidyl peptidase IV-related protein-1;
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DPP8 Protein, GST-tagged
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Dipeptidyl-Peptidase 8, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPP8 protein, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human DPP8
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DPP8 Protein
Source (Host):Species:Human
Product nameRecombinant Human DPP8 293 Cell Lysate
Source (Host):Species:Human
Product nameRecombinant Human DPP8 293 Cell Lysate
Source (Host):Species:
Product nameDPP8 Assay Kit

Protein Function

DPP8 has several biochemical functions, for example, dipeptidyl-peptidase activity, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DPP8 itself. We selected most functions DPP8 had, and list some proteins which have the same functions with DPP8. You can find most of the proteins on our site.
Related Protein
Function dipeptidyl-peptidase activity
Related Protein DPP3; DPP4; PRCP; DPP8; FAP; DPP7; DPEP3; NAALAD2; DPEP1; DPEP2
Function serine-type peptidase activity
Related Protein GZME; PRSS16; TRY; KLK1B24; ST14; TMPRSS11F; MCPT8; GZMB; GZMF; PRSS8

Interacting Protein

DPP8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPP8 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPP8.
CXCL11; CXCL10; p48061-1; p48061-2

DPP8 Related Articles

Justa-Schuch, D; Moller, U; et al. The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus. CELLULAR AND MOLECULAR LIFE SCIENCES 71:3611-3626(2014).
Harstad, EB; Rosenblum, JS; et al. DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues. REGULATORY PEPTIDES 186:26-35(2013).