elovl6
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  • Official Full Name
  • ELOVL fatty acid elongase 6
  • Background
  • Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]
  • Synonyms
  • ELOVL6; ELOVL fatty acid elongase 6; FAE; LCE; FACE; elongation of very long chain fatty acids protein 6; hELO2; ELOVL FA elongase 6; fatty acid elongase 2; fatty acyl-CoA elongase; long-chain fatty-acyl elongase; 3-keto acyl-CoA synthase ELOVL6; very-long-chain 3-oxoacyl-CoA synthase 6; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast);
Cat.#:ELOVL6-12422HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ELOVL6, GST-tagged
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Cat.#:ELOVL6-5152MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ELOVL6 Protein
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Cat.#:ELOVL6-2080RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ELOVL6 Protein
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Cat.#:ELOVL6-1454RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ELOVL6 Protein, His-tagged
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Cat.#:ELOVL6-3183CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ELOVL6
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Cat.#:ELOVL6-9938ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ELOVL6
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Involved Pathway

ELOVL6 involved in several pathways and played different roles in them. We selected most pathways ELOVL6 participated on our site, such as Fatty acid elongation, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELOVL6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fatty acid elongation
ELOVL1; ELOVL5; ELOVL2; MECR; ELOVL7B; HSD17B12; ELOVL7; HADHAB; ELOVL6; HADH
Biosynthesis of unsaturated fatty acids
ELOVL6; PECR; ACOX3; PTPLAD2; HADHA; HSD17B12; ELOVL2; BAAT; SCDB; SCD5
Fatty acid metabolism
ACSL1A; SCDB; ACADL; FADS2; EHHADH; MECR; SCD5; ACSL1B; PPT2; OXSM

Protein Function

ELOVL6 has several biochemical functions, for example, protein binding, transferase activity, transferring acyl groups other than amino-acyl groups. Some of the functions are cooperated with other proteins, some of the functions could acted by ELOVL6 itself. We selected most functions ELOVL6 had, and list some proteins which have the same functions with ELOVL6. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein MEF2D; SMARCE1; UBE2M; XPA; GATA5; NFKBID; ZWILCH; ELMO3; SIRT2; ZNF217
Function transferase activity, transferring acyl groups other than amino-acyl groups
Related Protein KAT7A; HTATIP; SCP2A; DGAT2L6; ACAA1A; MOGAT3A; KAT6A; ELOVL6; KAT7B

ELOVL6 Related Articles

Yamada, K; Mizukoshi, E; et al. Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis. LIVER INTERNATIONAL 35:582-590(2015).
Moon, YA; Ochoa, CR; et al. Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance. JOURNAL OF LIPID RESEARCH 55:2597-2605(2014).