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FAAH2

Official Full Name

fatty acid amide hydrolase 2
Overview

This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate.
Synonyms

FAAH2; fatty acid amide hydrolase 2; AMDD, amidase domain containing; fatty-acid amide hydrolase 2; FAAH 2; FLJ31204; RP11 479E16.1; oleamide hydrolase 2; amidase domain containing; anandamide amidohydrolase 2; amidase domain-containing protein; AMDD;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Homo sapiens (Human)
Human

Source

E.coli
E.coli expression system
HEK293
In Vitro Cell Free System
In vitro E. coli expression system
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FAAH2-3628H	Recombinant Human FAAH2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FAAH2-2459H	Recombinant human FAAH2, His-tagged	E.coli	His		Inquiry
Human	FAAH2-6480HCL	Recombinant Human FAAH2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	FAAH2-4419HF	Recombinant Full Length Human FAAH2 Protein, GST-tagged	In Vitro Cell Free System	GST	532 amino acids	Inquiry
Human	FAAH2-849H	Recombinant Human FAAH2 Full Length Transmembrane protein, His-tagged	In vitro E. coli expression system	His	1-532aa	Inquiry
Homo sapiens (Human)	RFL29064HF	Recombinant Full Length Human Fatty-Acid Amide Hydrolase 2(Faah2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-532aa)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
FAAH2 Related Articles

FAAH2 involved in several pathways and played different roles in them. We selected most pathways FAAH2 participated on our site, such as Arachidonic acid metabolism, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAAH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Arachidonic acid metabolism	CYP2U1;PTGIS;PTGESL;CYP2Y3;CYP4B1;CYP2AD2;ALOX15B;CYP2N13;ALOX12
Metabolism	SLC5A9;PROZA;SGMS2;MED29;VAPB;MMADHC;APOA4A;PTGR1;NUDT16
Metabolism of lipids and lipoproteins	CYP24A1;ACOT9.1;SREBF2;EBP;PTGR1;CYP27A1;LPA;SLC44A5B;MED22
anandamide degradation

FAAH2 has several biochemical functions, for example, carbon-nitrogen ligase activity, with glutamine as amido-N-donor, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FAAH2 itself. We selected most functions FAAH2 had, and list some proteins which have the same functions with FAAH2. You can find most of the proteins on our site.

Function	Related Protein
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	FAAH;GATB;FAAH2B;FAAH2;PET112L;FAAH2A
hydrolase activity	Ces2e;FAM105B;GZMF;C1rb;FURINB;MCPT9;PPP4CB;IDI2;MOGS

FAAH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAAH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAAH2.

Durinck, S; Stawiski, EW; et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma. NATURE GENETICS 47:13-+(2015).

Bennetzen, MF; Wellner, N; et al. Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss. INTERNATIONAL JOURNAL OF OBESITY 35:1377-1384(2011).