|Official Full Name||glutamate receptor, ionotropic, kainate 3|
|Background||Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.|
|Synonyms||GRIK3; glutamate receptor, ionotropic, kainate 3; glutamate receptor, ionotropic kainate 3; GLUR7; EAA5; Excitatory amino acid receptor 5; GLR 7; GLR7; GLU R7; GLUR 7; GluR 7a; GluR7a; Glutamate receptor 7; Glutamate receptor ionotropic kainate 3; GRIK 3; gluR-7; dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GRIK3 involved in several pathways and played different roles in them. We selected most pathways GRIK3 participated on our site, such as Neuroactive ligand-receptor interaction, Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Neuroactive ligand-receptor interaction||GALR2; CHRNE; DRD4B; NR3C1; TAAR14F; CHRNA10; GABRG1; TACR1A; CYSLTR2; CSH1|
|Glutamatergic synapse||SHANK2; HOMER2; GRM6; GRIN2C; GNG7; PPP3R2; GRIN1; SLC1A7; TRPC1; SLC1A3|
GRIK3 has several biochemical functions, for example, adenylate cyclase inhibiting G-protein coupled glutamate receptor activity, extracellular-glutamate-gated ion channel activity, glutamate receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIK3 itself. We selected most functions GRIK3 had, and list some proteins which have the same functions with GRIK3. You can find most of the proteins on our site.
|adenylate cyclase inhibiting G-protein coupled glutamate receptor activity||GRIK3|
|extracellular-glutamate-gated ion channel activity||GRIN1; GRIN3B; GRIA4; GRIK5; GRID2; GRIA1A; GRIA2; GRIN2C; GRIK3; GRIK4|
|glutamate receptor activity||GRM8; GRM2; GRIK3; GRM7; GRM3; GRM1; GRID2; GRIA1; GRM5; GRIK5|
|ion channel activity||CHRNB3; KCNV2; CATSPER2; KCNH1B; P2RX3A; KCNG4A; GRIA2B; KCNH5; AKR1C1; TRPM1A|
|ionotropic glutamate receptor activity||GRIN2BB; GRIK3; KBP; GRIA1B; GRIN2A; GRIA2A; GRID2; GRIA4B; GRIA4; GRIN3B|
|kainate selective glutamate receptor activity||GRIK2; GRIK3; GRIK1; GRIK5; GRIK4|
|protein binding||MCRS1; TBC1D15; CDC42EP4; ZBTB43; CENPO; TBC1D7; UQCC1; TEX19.1; ACTN2; ARFIP2|
|receptor activity||CD200R2; GRIN2BB; SELS; CD93; CD200R3; VMN1R46; CD244; ANTXR2B; GRIA2A; EIF2D|
GRIK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIK3.