Recombinant Human GRIK3 Protein, GST-tagged

• Cat.No.: GRIK3-5338H
• Product Overview: Human GRIK3 full-length ORF ( NP_000822.2, 1 a.a. - 919 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 130.4 kDa
• AA Sequence: MTAPWRRLRSLVWEYWAGLLVCAFW IPDSRGMPHVIRIGGIFEYADGPNA QVMNAEEHAFRFSANIINRNRTLLP NTTLTYDIQRIHFHDSFEATKKACD QLALGVVAIFGPSQGSCTNAVQSIC NALEVPHIQLRWKHHPLDNKDTFYV NLYPDYASLSHAILDLVQYLKWRSA TVVYDDSTGLIRLQELIMAPSRYNI RLKIRQLPIDSDDSRPLLKEMKRGR EFRIIFDCSHTMAAQILKQAMAMGM MTEYYHFIFTTLDLYALDLEPYRYS GVNLTGFRILNVDNPHVSAIVEKWS MERLQAAPRSESGLLDGVMMTDAAL LYDAVHIVSVCYQRAPQMTVNSLQC HRHKAWRFGGRFMNFIKEAQWEGLT GRIVFNKTSGLRTDFDLDIISLKED GLEKVGVWSPADGLNITEVAKGRGP NVTDSLTNRSLIVTTVLEEPFVMFR KSDRTLYGNDRFEGYCIDLLKELAH ILGFSYEIRLVEDGKYGAQDDKGQW NGMVKELIDHKADLAVAPLTITHVR EKAIDFSKPFMTLGVSILYRKPNGT NPSVFSFLNPLSPDIWMYVLLAYLG VSCVLFVIARFSPYEWYDAHPCNPG SEVVENNFTLLNSFWFGMGSLMQQG SELMPKALSTRIIGGIWWFFTLIII SSYTANLAAFLTVERMESPIDSADD LAKQTKIEYGAVKDGATMTFFKKSK ISTFEKMWAFMSSKPSALVKNNEEG IQRALTADYALLMESTTIEYVTQRN CNLTQIGGLIDSKGYGIGTPMGSPY RDKITIAILQLQEEDKLHIMKEKWW RGSGCPEEENKEASALGIQKIGGIF IVLAAGLVLSVLVAVGEFVYKLRKT AEREQRSFCSTVADEIRFSLTCQRR VKHKPQPPMMVKTDAVINMHTFNDR RLPGKDSMACSTSLAPVFP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GRIK3 glutamate receptor, ionotropic, kainate 3 [ Homo sapiens ]
• Official Symbol: GRIK3
• Synonyms: GRIK3; glutamate receptor, ionotropic, kainate 3; glutamate receptor, ionotropic kainate 3; GluK3; GLUR7; gluR-7; glutamate receptor 7; excitatory amino acid receptor 5; dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); EAA5; GLR7; GluR7a
• Gene ID: 2899
• mRNA Refseq: NM_000831
• Protein Refseq: NP_000822
• MIM: 138243
• UniProt ID: Q13003